Container having a sonication compartment

• US 4,720,374 A
• Filed: 07/22/1985
• Issued: 01/19/1988
• Est. Priority Date: 07/22/1985
• Status: Expired due to Term

• Current Assignee: Dade Behring, Inc. (Siemens AG)
• Original Assignee: E. I. du Pont de Nemours and Company (Corteva, Inc.)
• Inventors: Ramachandran, Narayanaswamy
• Primary Examiner(s): NOT, DEFINED
• Assistant Examiner(s): Johnson, William R.
• Application Number:
  US06/757,576
• Time in Patent Office: 911 Days
• Field of Search: 422/58, 422/61, 422/65, 422/102, 422/261, 422/266, 422/310, 422/128, 206/0.5, 206/524.7, 206/538, 206/539, 206/569, 220/213, 220/229, 220/359, 356/244, 356/246, 435/805
• US Class Current: 422/310
• CPC Class Codes: B01F 2101/23 Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
• CPC Class Codes: B01L 2300/0609 Holders integrated in container to position an object
• CPC Class Codes: B01L 2300/0858 Side walls
• CPC Class Codes: B01L 2400/086 using baffles or other fixed flow obstructions
• CPC Class Codes: B01L 3/5085 for multiple samples, e.g. microtitration plates
• CPC Class Codes: G01N 2035/0436 with pre-packaged reagents, i.e. test-packs

Abstract

A container for the dissolution of a tablet of material is characterized by a plurality of projections mounted within the container. The projections cooperate to define a tablet-receiving recess adapted to confine a tablet inwardly therewithin in a relatively high energy zone during sonication of the tablet. Gaps between the projections define recirculating liquid channels whereby hydrating liquid passing through the tablet-receiving recess may be recirculated to other regions of the compartment.

Claims

1. A container having a hydration compartment adapted to receive therein a hydrating liquid and a material to be dissolved or dispersed thereinto, the compartment having sidewalls and endwalls and a floor from which an array of finger-like members project vertically upwardly into the compartment, the fingers being spaced from the sidewalls and endwalls with the tips of predetermined ones of the finger-like members being above the tips of others of the members within the compartment, the members being arranged with respect to each other to define a material receiving recess and being relatively spaced apart to define recirculating gaps therebetween such that, in use, the material to be dissolved by the application of ultrasonic energy from a source introduced into the compartment is confined within a relatively high energy zone defined by the recess and hydrating fluid is recirculated through and out of the relatively high energy zone through the gaps between the finger-like members.

2. The container of claim 1 further comprising planar members having side surfaces extending substantially perpendicularly of the floor, the planar members being oriented substantially on diagonals of the compartment.