Novel 2-phenyl-imidazoles and pharmaceutical compositions containing same
First Claim
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1. A compound of the formula ##STR15## wherein (a) A is nitrogen, B is hydroxymethine and D is methine;
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R1 is methylmercapto, methylsulfinyl, methylsulfonyl, aminosulfonyl, methylaminosulfonyl or dimethylaminosulfonyl;
R2 is alkoxy of 1 to 3 carbon atoms; and
R3 is hydrogen or methoxy;
a pyridone tautomer thereof;
or a non-toxic, pharmacologically acceptable acid addition salt thereof.
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Abstract
The invention relates to novel 2-phenyl-imidazoles of the formula ##STR1## and the tautomers and acid addition salts thereof, particularly the pharmacologically acceptable acid addition salts, which exhibit valuable pharmacological properties, particularly an effect on the contractility of the heart muscle. The compounds of Formula I may be prepared by methods conventionally used for similar compounds.
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Citations
11 Claims
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1. A compound of the formula ##STR15## wherein (a) A is nitrogen, B is hydroxymethine and D is methine;
- or
(b) B is nitrogen, one of A and D is hydroxymethine and the other is methine; R1 is methylmercapto, methylsulfinyl, methylsulfonyl, aminosulfonyl, methylaminosulfonyl or dimethylaminosulfonyl; R2 is alkoxy of 1 to 3 carbon atoms; and R3 is hydrogen or methoxy; a pyridone tautomer thereof;
or a non-toxic, pharmacologically acceptable acid addition salt thereof. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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Specification