Urine drainage bag outlet with barrier against microbial infection

• US 4,723,950 A
• Filed: 02/20/1987
• Issued: 02/09/1988
• Est. Priority Date: 12/12/1984
• Status: Expired due to Term

• Current Assignee: C.R. Bard, Inc. (Becton, Dickinson & Co)
• Original Assignee: C.R. Bard, Inc. (Becton, Dickinson & Co)
• Inventors: Lee, Clarence C.
• Primary Examiner(s): NOT, DEFINED
• Assistant Examiner(s): NOT, DEFINED
• Application Number:
  US07/018,787
• Time in Patent Office: 354 Days
• Field of Search: 604/317, 604/318, 604/327, 604/333, 604/322, 604/890, 604/892
• US Class Current: 604/322
• CPC Class Codes: A61F 5/441 having venting or deodorant means, e.g. filters ; having antiseptic means, e.g. bacterial barriers
• CPC Class Codes: A61M 1/882 Draining devices provided with means for releasing antimicrobial or gelation agents in the drained fluid

Abstract

A urine drainage bag having an outlet tube housing a microcidal tube is disclosed. The microcidal tube is manufactured from polymeric materials capable of absorbing and releasing antimicrobial substances in a controllable sustained time release mechanism, activated upon contact with droplets of urine, thereby preventing the retrograde migration of infectious organisms into the drainage bag.

Claims

1. An outlet for a urine drainage bag, comprising:

an outlet tube secured to the bottom part of the urine drainage bag; and

an independently formed microbicidal tube housed in and connected to the interior of the outlet tube, comprising means for storing and means for releasing one or more microbicidal substances, said means for storing the microbicidal substance/s being a porous material, said means of releasing the microbicidal substance/s being a hydrophilic polymer which in response to contact with urine swells causing the leaching out of the microbicidal substance, said microbicidal substance capable of being passively and controllably released in a long term sustained time sequence without human intervention to create an effective barrier against movement and multiplication or organisms and subsequent infection of the urinary tract.

2. The outlet according to claim 1 wherein the means of storing the microbicidal substance/s is a porous polypropylene material.

3. The outlet according to claim 1 wherein the hydrophylic polymer is D-3 polyethylene glycol polyurethane.

4. The outlet according to claim 1 wherein the microbicidal substances are hexachlorophene, gentamycin and clotrimazol.

5. The outlet according to claim 1 wherein the microbicidal substances are triclosan, chloroxin and tolnaftate.

6. The outlet according to claim 1 wherein the microbicidal substances are nalidixic acid and parachlorometaxylenol.

7. The outlet according to claim 1 wherein the microbicidal substances are zinc pyrithione and tetracycline.

8. The outlet according to claim 1 wherein the microbicidal substances are gentamycin and zinc pyrithione.

9. The outlet according to claim 1 wherein the microbicidal substances are tetracycline polymyxin and zinc pyrithione.

10. The outlet according to claim 1 wherein the microbicidal substances are gentamycin and parachlorometaxylenol.

11. The outlet according to claim 1 wherein the microbicidal substances are tetracycline, parachlorometaxylenol, clotrimazol and tolnaftate.

12. The outlet according to claim 1 wherein the microbicidal substances are triclosan and chloroxin.

13. The outlet according to claim 1 wherein the microbicidal substances are chlordexidine and triclosan.

14. The outlet according to claim 1 wherein the microbicidal substances are chloroform, hexachlorophene, nalidixic acid, clotrimazol and tolnaftate.

15. The outlet according to claim 1 wherein the microbicidal substances are parachlorometaxylenol, chlorhexidine and nitrofurazone.

16. The outlet according to claim 1 wherein the microbicidal substances are hexachlorophane, clotrimazol and aminacrine.

17. The outlet according to claim 1 wherein the microbicidal substances are hexachlorophene, and clotrimazol.

18. The outlet according to claim 1 wherein the microbicidal substances are triclosan, hexachlorophene, clotrimazole and nitrofurazano.

19. A method of treating the outlet tube of a urinary drainage bag to prevent passage and/or growth of microorganisms comprising:

the insertion of a microbicidal tube inside the outlet tube, said microbicidal tube being porous with a hydrophilic polymer disposed throughout and containing at least one microbicidal substance, whose release is passively activated during drainage of urine, the hydrophilic polymer in response to contact with urine swells causing leaching out of the microbicidal substance, whereby it acts upon the present microorganisms without human intervention to create an effective barrier against movement and multiplication of organisms and subsequent infection of the urinary tract.

20. A urinary drainage system comprising a sustained time release barrier incorporated therein, said barrier comprising means for storing and means for passively and controllably releasing at least one microbicidal substance, said means for storing the microbicidal substance/s being a porous material, said means of releasing the microbicidal substance/s being a hydrophilic polymer which in response to contact with urine swells causing the leaching out of the microbicidal substance, said microbicidal substance capable of being passively and controllably released in a long term sustained time sequence without human intervention to create an effective barrier against movement and multiplication of organisms and subsequently infection of the urinary tract.

21. The urinary drainage system according to claim 20 wherein the means of storing the microbicidal substance/s is a porous polypropylene material.

22. The urinary drainage system according to claim 20 wherein the hydrophilic polymer is D-3 polyethylene glycol polyurethane.

23. The urinary drainage system according to claim 20 wherein the microbicidal substances are hexachlorophene, gentamycin and clotrimazole.

24. The urinary drainage system according to claim 20 wherein the microbicidal substances are triclosan, chloroxin and tolnaftate.

25. The urinary drainage system according to claim 20 wherein the microbicidal substances are nalidixic acid and parachlorometaxylenol.

26. The urinary drainage system according to claim 20 wherein the microbicidal substances are zinc pyrithione and tetracycline.

27. The urinary drainage system according to claim 20 wherein the microbicidal substances are gentamycin and zinc pyrithione.

28. The urinary drainage system according to claim 20 wherein the microbicidal substances are tetracycline polymyxin and zinc pyrithione.

29. The urinary drainage system according to claim 20 wherein the microbicidal substances are gentamycin and parachlorometaxylenol.

30. The urinary drainage system according to claim 20 wherein the microbicidal substances are tetracycline, parachlorometaxylenol, clotrimazol and tolnaftate.

31. The urinary drainage system according to claim 20 wherein the microbicidal substances are triclosano and chloroxin.

32. The urinary drainage system according to claim 20 wherein the microbicidal substances are chlordexidine and triclosan.

33. The urinary drainage system according to claim 20 wherein the microbicidal substances are chloroform, hexachlorophene, nalidixic acid, clotrimazol and tolnaftate.

34. The urinary drainage system according to claim 20 wherein the microbicidal substances are parachlorometaxylenol, chlorhexidine and nitrofurazone.

35. The urinary drainage system according to claim 20 wherein the microbicidal substances are hexachlorophane, clotrimazol and aminacrine.

36. The urinary drainage system according to claim 20 wherein the microbicidal substances are hexachlorophene, and clotrimazol.

37. The urinary drainage system according to claim 20 wherein the microbicidal substances are triclosan, hexachlorophene, clotrimazole and nitrofurazano.

38. A microbicidal tube, comprising means for storing and means for releasing one or more antimicrobial substance/s capable of being passively and controllably released in a sustained time sequence, said means for storing the microbicidal substance/s being a porous material, said means of releasing the microbicidal substance/s being a hydrophilic polymer which in response to contact with urine swells causing the leaching out of the microbicidal substance said microbicidal substance capable of being passively and controllably released in a long term sustained time sequence without human intervention to create an effective barrier against movement and multiplication of organisms and subsequently infection of the urinary tract.

39. The microcidal tube according to claim 38, wherein the means of storing the microbicidal substance/s is a porous polypropylene material.

40. The microbicidal tube according to claim 38 wherein the hydrophilic polymer is D-3 polyethylene glycol polyurethane.

41. The microbicidal tube according to claim 38 wherein the microbicidal substances are hexachlorophene, gentamycin and clotrimazol.

42. The microbicidal tube according to claim 38 wherein the microbicidal substances are triclosan, chloroxin and tolnaftate.

43. The microbicidal tube according to claim 38 wherein the microbicidal substances are nalidixic acid and parachlorometaxylenol.

44. The microbicidal tube according to claim 38 wherein the microbicidal substances are zinc pyrithione and tetracycline.

45. The microbicidal tube according to claim 38 wherein the microbicidal substances are gentamycin and zinc pyrithione.

46. The microbicidal tube according to claim 38 wherein the microbicidal substances are tetracycline polymyxin and zinc pyrithione.

47. The microbicidal tube according to claim 38 wherein the microbicidal substances are gentamycin and parachlorometaxylenol.

48. The microbicidal tube according to claim 38 wherein the microbicidal substances are tetracycline, parachlorometaxylenol, clotrimazol and tolnaftate.

49. The microbicidal tube according to claim 38 wherein the microbicidal substances are triclosano and chloroxin.

50. The microbicidal tube according to claim 38 wherein the microbicidal substances are chlordexidine and triclosan.

51. The microbicidal tube according to claim 38 wherein the microbicidal substances are hexachlorophene, nalidixic acid, clotrimazol and tolnaftate.

52. The microbicidal tube according to claim 38 wherein the microbicidal substances are parachlorometaxylenol, chlorhexidine and nitrofurazone.

53. The microbicidal tube according to claim 38 wherein the microbicidal substances are hexachlorophane, clotrimazol and aminacrine.

54. The microbicidal tube according to claim 38 wherein the microbicidal substances are hexachlorophene, and clotrimazol.

55. The microbicidal tube according to claim 38 wherein the microbicidal substances are triclosan, hexachlorophene, clotrimazole and nitrofurazano.