Method and apparatus for low energy endocardial defibrillation

• US 4,727,877 A
• Filed: 08/12/1986
• Issued: 03/01/1988
• Est. Priority Date: 12/18/1984
• Status: Expired due to Fees

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Kallok, Michael J.
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US06/894,753
• Time in Patent Office: 567 Days
• Field of Search: 128/419 D
• US Class Current: 607/5
• CPC Class Codes: A61N 1/3918 characterised by shock pathway, e.g. by electrode configuration
• CPC Class Codes: A61N 1/3956 Implantable devices for applying electric shocks to the heart, e.g. for cardioversion

Abstract

Ventricular fibrillation and other tachyarrhythmias are controlled by delivery of two sequential impulses to two pairs of electrodes placed partially within or adjacent to the heart. One electrode pair is provided by an endocardial lead which includes a distal electrode adapted to reside in the apex of the right ventricle and a proximal electrode designed to lie in the superior vena cava. The second electrode pair comprises the distal electrode within the right ventricle and a further electrode lodged in or adjacent to the coronary sinus. The metal case of the implantable pulse generator which supplies pulses to the electrode pairs may be substituted for the coronary sinus electrode if the pulse generator is implanted above and to the left of the heart in the left pectoral region of the patient'"'"'s body. Alternatively, a subcutaneous plate electrode may be substituted for the can, obviating the need for implanting the generator in the left pectoral region. The system also works for temporary use with a skin electrode pair with the catheter in conjunction with an external defibrillator. This disposition of electrode pairs produces a temporal and spatial summation of the delivered energy which results in a reduction in the energy required for defibrillation or cardioversion, and allows the use of less traumatic surgical procedures than epicardial lead systems.

Claims

1. A method for controlling cardiac ventricular fibrillation or other tachyarrhythmias by passing an electric current through the heart which comprises:

disposing a first electrode pair along the longitudinal axis of the heart;

disposing a second electrode pair laterally between the ventricle and the region of the coronary sinus of the heart; and

sequentially pulsing each of said electrode pairs at a voltage or voltages providing a temporal and spatial summation of delivered current above the threshold level sufficient to effect defibrillation or cardioversion of the heart.

2. The method of claim 1 wherein said pulses are separated by an interval of at least about 0.1 ms.

3. The method of claim 1 wherein said pulses are separated by an interval of about 0.1 ms to about 2 ms.

4. The method of claims 1, 2 or 3 wherein said pulses have a duration of about 2 ms to about 8 ms.

5. The method of claim 1 wherein the sequential pulsing step comprises subjecting each of said pairs of electrodes in sequence to an electrical pulse at a voltage between about 100 and about 500 volts for a duration between about 2 and about 8 ms, the pulses being separated by an interval of about 0.1 ms to about 2 ms.

6. A method for controlling cardiac ventricular fibrillation or other tachyarrhythmias by passing an electric current through the heart which comprises:

disposing a first electrode in the right ventricle of the heart;

disposing a second electrode in the region of the superior vena cava;

disposing a third electrode in the region of the coronary sinus of the heart; and

sequentially applying pulses between said first and second electrodes and said first and third electrodes at a voltage or voltages providing a temporal and spatial summation of delivered current above the threshold level sufficient to effect defibrillation or cardioversion of the heart.

7. The method of claim 6 wherein said pulses are separated by an interval of at least about 0.1 ms.

8. The method of claim 6 wherein said pulses are separated by an interval of about 0.1 ms to about 2 ms.

9. The method of claims 6, 7 or 8 wherein said pulses have a duration of about 2 ms to about 8 ms.

10. The method of claim 6 wherein the sequential pulsing step comprises subjecting each of said pairs of electrodes in sequence to an electrical pulse at a voltage between about 100 and about 500 volts for a duration between about 2 and about 8 ms, the pulses being separated by an interval of about 0.1 ms to about 2 ms.

11. The method of claim 6 wherein the step of disposing a third electrode in the region of the coronary sinus further comprises:

disposing said third electrode through the venous system and into the lumen of the coronary sinus.

12. The method of claim 6 wherein the step of disposing a third electrode in the region of the coronary sinus further comprises:

disposing said third electrode epicardially alongside the coronary sinus.

13. The method of claim 6 wherein the step of disposing a third electrode in the region of the coronary sinus further comprises:

disposing said third electrode subcutaneously in the left pectoral region of the body.

14. The method of claim 6 wherein the step of disposing a third electrode in the region of the coronary sinus further comprises:

disposing said third electrode on the surface of the body overlying the left pectoral region.

15. Apparatus for controlling cardiac ventricular fibrillation or other tachyarrhythmias by passing an electrical current through the heart which comprises:

means disposing a first pair of electrodes axially along the heart between the atrium and ventricle;

means disposing a second pair of electrodes between the ventricle and the region of the coronary sinus; and

means for sequentially pulsing each of said pairs of electrodes at a voltage or voltages providing a temporal and spatial summation of the delivered current above the threshold level sufficient to effect defibrillation or cardioversion of the heart.

16. The apparatus of claim 15 wherein said pulses are separated by an interval of at least about 0.1 ms.

17. The apparatus of claim 15 wherein said pulses are separated by an interval of about 0.1 ms to about 2 ms.

18. The apparatus of claim 15, 16 or 17 wherein each of said pulses has a duration of about 2 ms to about 8 ms.

19. The apparatus of claim 15 wherein the sequential pulsing means comprises means for subjecting each of said pairs of electrodes in sequence to an electrical pulse at a voltage between about 100 and about 500 volts for a duration between about 2 and about 8 ms, the pulses being separated by an interval of about 0.1 ms to about 2 ms.

20. The apparatus of claim 15 or 19 wherein;

said means disposing said first pair of electrodes further disposes a first electrode in the right ventricle of the heart and a second electrode in the region of the superior vena cava; and

wherein said second pair of electrodes disposed between the right ventricle and the region of the coronary sinus further comprises the first electrode of the first electrode pair and means disposing a third electrode in the region of the coronary sinus.

21. The apparatus of claim 20 further comprising means for disposing said third electrode transvenously into the lumen of the coronary sinus.

22. The apparatus of claim 21 further comprising means for disposing said third electrode epicardially adjacent to the coronary sinus.

23. The apparatus of claim 21 further comprising means for disposing said third electrode subcutaneously in the left pectoral region of the heart.

24. The apparatus of claim 21 further comprising means for disposing said third electrode on the surface of the body overlying the left pectoral region.