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Method of treating wounds with granules and dressing

  • US 4,728,642 A
  • Filed: 04/29/1985
  • Issued: 03/01/1988
  • Est. Priority Date: 04/22/1982
  • Status: Expired due to Term
First Claim
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1. The method of treating a dermal ulcer emitting a large amount of exuadate comprising packing the ulcer with granules capable of interacting with the exudate and then overlaying the ulcer with an occlusive dressing having an adhesive layer which also is capable of reacting with the exudate and of forming a bond with the normal skin surrounding said ulcer wherein said granules have a particle size of from about 10 to about 40 mesh and consist essentially of one or more water dispersible hydrocolloids selected from the group consisting of sodium carboxymethylcellulose, calcium carboxymethylcellulose, pectin, gelatin, guar gum, locust bean gum, collagen and gum karaya, and from zero to 50% by weight of one or more water swellable cohesive strengthening agents, one or more hydratable polymers, and mixtures thereof wherein said water swellable cohesive strengthening agents if present are selected from the group consisting of water-insoluble cross-linked sodium carboxymethylcellulose, water-insoluble starch-acrylonitrile graft copolymer, and water-insoluble cross-linked dextran and wherein said hydratable polymers if present are selected from the group consisting of gluten and long chain polymers of methyl vinyl ether/maleic acid and wherein said occulusive dressing is a multi-layered dressing consisting essentially of an adhesive layer which in use contacts the wound and the surrounding normal skin, an intermediate layer of semi-open cell polymeric foam bonded to the upper surface of said adhesive layer, and an outer moisture impervious polymeric film coated or laminated to the upper surface of said foam layer, wherein said wound and skin contacting adhesive layer consists of from about 35% to about 50% by weight of low molecular weight polyisobutylenes and from about 45% to about 65% by weight of one or more water dispersible hydrocolloids selected from the group consisting of sodium carboxymethylcellulose, calcium carboxymethylcellulose, pectin, gelatin, guar gum, locust bean gum, collagen, and gum karaya.

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