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Process for producing .alpha.-aspartyl-phenylalanine ester

  • US 4,730,076 A
  • Filed: 12/16/1986
  • Issued: 03/08/1988
  • Est. Priority Date: 12/18/1985
  • Status: Expired due to Fees
First Claim
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1. A process for producing α

  • -aspartyl-phenylalanine ester represented by the general formula (I) ##STR10## wherein R'"'"' represents an alkyl group having 1 to 4 carbon atoms, which comprises reducing an N-protected-N-hydroxymethyl-α

    -aspartyl-phenylalanine ester represented by the general formula (IV) ##STR11## wherein R represents an organic moiety which can be substituted by hydrogen reductively, and R'"'"' is as defined above, with hydrogen gas or formic acid in the presence of a reduction catalyst and an aromatic primary amine.

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