Laser system for providing target specific energy deposition and damage

• US 4,733,660 A
• Filed: 12/10/1986
• Issued: 03/29/1988
• Est. Priority Date: 08/07/1984
• Status: Expired due to Fees

• Current Assignee: Medical Laser Research and Development Corporation
• Original Assignee: Medical Laser Research and Development Corporation
• Inventors: Itzkan, Irving
• Primary Examiner(s): HINDENBURG, MAX F
• Application Number:
  US06/940,195
• Time in Patent Office: 475 Days
• Field of Search: 128/4-8, 128/303.1, 128/395-398, 219/121 LA, 219/121 LR, 219/121 LU, 219/121 LV
• US Class Current: 606/9
• CPC Class Codes: A61B 18/203 applying laser energy to the outside of the body
• CPC Class Codes: A61B 2017/00756 Port wine stains
• CPC Class Codes: A61B 2018/00005 Cooling or heating of the probe or tissue immediately surrounding the probe
• CPC Class Codes: A61B 2018/00029 open
• CPC Class Codes: A61B 2018/00452 Skin
• CPC Class Codes: A61B 2018/00458 Deeper parts of the skin, e.g. treatment of vascular disorders or port wine stains
• CPC Class Codes: A61B 2018/20351 Scanning mechanisms

Abstract

A hand piece for use with a laser includes a scanning mechanism which controls dosimetry of radiation applied to a target area which is adjustable to limit thermal diffusion from the light absorbing portion of the irradiated target site for selective target specific energy deposition. When used for dermatologic purposes, the adjustable scanning mechanism permits radiation to impinge on tissue for a predetermined period of time for the selective necrosis of highly-filled blood vessels, while leaving adjacent tissue and empty blood vessels undamaged. The dwell time of the laser beam is designed to match the diffusion time for thermal destruction of the wall of the abnormal vessel, with the dwell time adjusted by the scanning rate.

Claims

1. A system for use in living tissue or cells in the medical treatment of certain conditions by the selective necrosis of a target material including blood vessels, melanin bearing, or other naturally or artificially pigmented tissues or cells, said system comprising:

means including a laser for generating a beam of laser radiation;

a housing;

laser beam applying means within said housing, in communication with said laser beam generating means, for controlling the dosimetry of laser radiation applied to the target material, said applying means including;

means within said housing for directing the beam of laser radiation along an optical path within said applying means;

means within said housing, positioned along the optical path, for focusing the beam of laser radiation onto the target material as a focused spot of laser radiation having a desired shape, dimension and intensity;

scanning means, within said housing and coupled to said directing means and to said focusing means, for automatically causing the laser beam to deviate from its optical path in such a way that the focused spot of laser radiation is moved at a rate in a desired pattern within an area containing the target material; and

means for controlling the rate at which the scanning means moves the focused laser radiation spot, and the intensity of the radiation in the focused laser spot, thereby controlling the laser energy absorbed by the target material by regulating a dwell time of the focused laser spot to produce a thermal diffusion into the target material, which causes necrosis of the target material while tissues and cells other than the target material are substantially unaffected.

2. The system of claim 1, wherein the dwell time is adjusted to match the thermal diffusion time for heat within the target material.

3. The system of claim 1, wherein the dwell time is sufficient to provide thermal diffusion into collagen positioned adjacent to the target material.

4. The system of claim 1, wherein the dwell time is sufficient relative to the intensity of the laser radiation to raise the temperature of the target material for a sufficient length of time to produce thermal necrosis thereof.

5. The system of claim 4, wherein said focussing means includes means for defining laser radiation intensity as a function of spot diameter and a depth of field of the laser radiation as focused to the spot.

6. The system of claim 1, wherein the controlling means regulates the scanning means to move the spot of laser radiation at a rate to achieve the desired dwell time.

7. The system of claim 1 wherein said housing is configured and sized for hand operation.

8. The system of claim 1 wherein said laser beam applying means is provided with cooling means.

9. The system of claim 1 wherein said scanning means causes the focused spot of laser radiation to move in a circular pattern on the target material.

10. The system of claim 9 wherein said scanning means comprises a hollow rotatable shaft having an access;

said system further comprises means for rotating said shaft; and

said focusing means is mounted in said hollow shaft at a non-perpendicular angle to said access, so as to provide a rotary scan of the focused spot on the target material as said shaft is rotated.

11. The system of claim 10 wherein said focusing means is a lens.

12. The system of claim 9 wherein said scanning means comprises a hollow rotatable shaft having an access, and an optical wedge mounted in said hollow shaft;

said system further comprising means for rotating said shaft; and

said focusing means including a fixed lens located after the optical wedge in the optical path.