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Multiwell membrane filtration apparatus

  • US 4,734,192 A
  • Filed: 06/21/1985
  • Issued: 03/29/1988
  • Est. Priority Date: 07/01/1982
  • Status: Expired due to Fees
First Claim
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1. A filtration apparatus able to retain liquid for extended periods of time comprising:

  • a plate having a thickness and a plurality of apertures extending through the thickness of the plate;

    filtration means comprising a member selected from the group consisting of a microporous membrane and an ultrafiltration membrane disposed over one end of each of said apertures such that a plurality of wells each having a discrete filtering area are formed;

    a hydrophobic fabric attached to said filtration means adjacent to said filtering areas and spaced apart from said filtering areas, said filtering areas and hydrophobic fabric defining spaces where liquid can be retained, said hydrophobic fabric positioned to prevent liquid placed in said wells from passing through said filtration means and said hydrophobic fabric by capillary action and gravity flow;

    operably connected means for applying a differential pressure across said filtering areas and said hydrophobic fabric for effecting passage of said liquid sequentially through a said filtering area, said filtration means, a said space and said hydrophobic fabric;

    a second plate defining a plurality of chambers, only one chamber being associated with each of said apertures, and operably connected means for providing that only one said chamber receives all liquid passing through the associated aperture.

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