Dialysis solution mixing system

• US 4,734,198 A
• Filed: 02/06/1984
• Issued: 03/29/1988
• Est. Priority Date: 02/06/1984
• Status: Expired due to Term

• Current Assignee: Minntech Corporation
• Original Assignee: Minntech Corporation
• Inventors: Martinez, F. Jesus, Cracauer, Raymond F., Caine, Earnest R., Harm, William H., Cosentino, Louis C., Fuller, Larry E.
• Primary Examiner(s): Spear, Frank
• Application Number:
  US06/577,387
• Time in Patent Office: 1,513 Days
• Field of Search: 210/321.3, 210/96.2, 210/206, 210/282, 210/647, 366/159, 422/281, 422/283
• US Class Current: 210/647
• CPC Class Codes: A61M 1/1656 Apparatus for preparing dialysates
• CPC Class Codes: A61M 1/1666 by dissolving solids
• CPC Class Codes: A61M 1/1668 Details of containers
• CPC Class Codes: B01F 21/20 using flow mixing
• CPC Class Codes: B01F 21/30 Workflow diagrams or layout of plants, e.g. flow charts; Details of workflow diagrams or layout of plants, e.g. controlling means
• CPC Class Codes: B01F 25/53 in which the mixture is discharged from and reintroduced into a receptacle through a recirculation tube, into which an additional component is introduced
• CPC Class Codes: B01F 35/7179 using sprayers, nozzles or jets

Abstract

A system and process for preparation of dialysis solution from dry chemicals and water on a large scale batch basis. The required amount of water is metered into a dialysis solution tank. Water from the tank is pumped into a spray head which is positioned above a shipping drum containing predetermined amounts of chemicals. Water rains down on the chemicals dissolving and/or entraining the same and the resulting slurry is returned to the dialysate tank as a slurry by means of a pickup wand and suction source. The liquid and chemicals in the dialysis solution tank are continually cycled until all the chemicals in the drum have been removed. Typically, an additional drum containing other kinds of chemicals is then added to the dialysis solution tank in the same manner. Circulation of the solution is continued within the tank until a fully uniform solution results. Dialysis solution in the tank is then filtered and checked for conductivity prior to its direct use in hemodialysis or dilution in a conventional proportioning system.

Claims

1. A blending system for preparation of dialysis solution from water and dry chemicals comprising:

(a) a dialysis solution tank;

(b) diluent means for supplying water into said tank;

(c) slurry means for conveying liquid from said tank to a source of dry chemicals, said slurry means including a chamber defining means for directing water onto said chemicals within said source container;

(d) said chamber defining means being constructed and arranged such that water is forced through a plurality of perforations in a plate forming the bottom of said chamber defining means so as to form a slurry of chemicals therebelow;

(e) suction means for conveying said slurry from said source to said dialysis solution tank including a hollow tubular pickup tube and a suction source;

(f) dialysis solution tank mixing means for mixing said chemicals within said tank; and

(g) delivery means for delivering mixed dialysis solution from said tank to a dispensing station.

2. The blending system of claim 1 wherein said mixing means includes a hollow toroidal ring within said tank and having a plurality of perforations, said toroidal ring being connected in fluid relation to the output from said suction means such that a slurry of water and chemicals enters said toroidal ring and passes through said perforations into said tank.

3. The blending system of claim 2 wherein said chamber defining means includes a chamber having a lower lip constructed and arranged such that said chamber is positionable above the upper rim of said chemical source container.

4. The blending system of claim 2 wherein said mixing means includes air bleed means being constructed and arranged for controllably introducing air into said toroidal ring so as to increase the agitation and mixing within said ring and tank.

5. The blending system of claim 2 wherein said suction means hollow tubular pickup tube includes a tip projecting beyond the open suction end of said tube such that said tip rests directly on the surface of said dry chemicals thereby functioning as a vacuum breaker if no slurry is present above the dry chemicals.

6. A blending system for preparation of hemodialysis solution from a diluent of water and from dry chemicals comprising:

(a) a dialysis solution tank;

(b) diluent means for supplying water into said tank;

(c) level sensing means within said tank for determining when said tank is charged with diluent and for controlling the flow of diluent into said tank;

(d) delivery means for conveying liquid within said tank to a source of a predetermined quantity of dry chemicals having the amount of chemicals required to make up the hemodialysis solution;

(e) said delivery means including solubilizing means to direct said diluent onto said dry chemicals so as to form a slurry of chemicals and diluent;

(f) level sensing means for controlling the introduction of diluent into said source of dry chemicals;

(g) pickup wand means for conveying said slurry and diluent from said chemical source to said dialysis solution tank;

(h) dialysis solution tank mixing means for receiving and mixing said chemicals within said tank from said pickup wand means; and

(i) dialysis solution delivery means for delivering mixed dialysis solution from said dialysis solution tank for dialysis including filters, pressure sensors, monitors for determining the concentration of said dialysis solution and valves controlled by outputs of said sensors and monitors.

7. A system for preparing dialysis solution from diluent water and dry chemicals comprising:

(a) a dialysis solution tank;

(b) diluent means for supplying water into said tank;

(c) a source of dry chemicals;

(d) delivery means for conveying diluent within said tank to said source of chemicals;

said delivery means including a spray head means for directing a spray of diluent into said source of dry chemicals so as to cause the chemicals to dissolve and form a slurry;

(e) pickup wand means for conveying said slurry within said chemical source to said dialysis solution tank;

(f) dialysis solution tank mixing means for receiving said slurry from said pickup wand means and for mixing same within said tank; and

(g) dialysis solution delivery means for delivering mixed dialysis solution from said dialysis solution tank for use in dialysis.

8. A system for preparation of hemodialysis solution from water and chemicals comprising:

(a) a dialysis solution tank including a water inlet and drain outlet;

(b) diluent means for supplying water into said tank through said water inlet;

(c) delivery means for conveying water within said tank through said drain outlet and into a container of dialysis solution chemicals so as to solubilize and entrain said chemicals in a slurry;

(d) wand means for conveying said slurry within said container into said dialysis solution tank;

(e) dialysis solution tank mixing means for mixing said slurried chemicals within said dialysis solution tank; and

(f) dialysis solution delivery means for delivering mixed dialysis solution from said dialysis solution tank for use in dialysis.

9. The system of claim 8 wherein said diluent means includes valve means for controlling fluid flow to said tank, said valve means being connected to a control means which opens and closes said valve means in response to a signal from a level sensor means within said tank.

10. The system of claim 8 wherein said delivery means includes valve means for controlling fluid flow from said tank, said valve means being connected to a control means which controls said valve means in response to a signal from a level sensor means associated with said drain outlet.

11. The system of claim 8 wherein said delivery means includes a spray head means for directing a spray of water into said container of dialysis solution chemicals so as to cause the chemicals to dissolve and become suspended in said water.

12. The system of claim 11 wherein said spray head means includes a spray head comprising a spray plate constructed and arranged to be positionable above an open salt container and having a plurality of perforations therethrough, such that water may pass in a relatively uniform, rain-like spray over the upper surface of chemicals within said container.

13. The system of claim 12 wherein said spray head further includes an opening through said spray plate through which said wand means may extend therethrough into said container, said opening being defined by an upstanding raised lip such that water passes through said perforations but not through said opening.

14. The system of claim 12 wherein said spray head includes a level sensor which extends below said spray plate into the container, said level sensor being constructed and arranged for sending a signal to a control means which controls the delivery of water into said container by controlling said delivery means.

15. The system of claim 14 wherein said spray head means includes an extension means for positioning said spray plate above the container and being constructed and arranged such that water passing through said spray plate perforations is directed within said container.

16. The system of claim 14 wherein said spray head means includes a container height extender, said extender being constructed and arranged with vertically extending walls that are supported by the top rim of said container such that the effective height of the container above the chemicals therewithin is increased, said height extender further being constructed and arranged such that a water proof liner within said chemical container may be pulled up and over said extender such that a waterproof barrier is formed above the level of the chemicals therewithin.

17. The system of claim 15 wherein said spray head means includes a cover means for excluding dust and containing splashed water and said cover means being constructed and arranged with a perforation through which said wand may pass therethrough.

18. A method for preparing hemodialysis solution from a diluent of water and from dry chemicals comprising:

(a) metering diluent into a dialysis solution tank;

(b) conveying said diluent from said tank onto a source of a predetermined quantity of dry chemicals having the amount of chemicals required to make up the hemodialysis solution;

(c) conveying the solubilized and dispersed chemicals from said source to said dialysis solution tank;

(d) mixing said diluent and chemicals within said dialysis solution tank;

(e) continuing said conveying of diluent which now contains chemicals from said tank to said chemical source and said slurried chemicals to said dialysis solution tank until all of said chemicals have been conveyed to said tank; and

(f) mixing said chemicals within said tank until a uniform concentration is obtained therewithin.

19. A method for preparing hemodialysis solution from a diluent of water and from dry chemicals comprising:

(a) filling a dialysis solution tank with a predetermined amount of water;

(b) conveying said water from said tank into a predetermined quantity of dry chemicals within a container on top of said chemicals;

(c) conveying the solutilized and dispersed chemicals within said container to said dialysis solution tank continuously during the conveyance of water and water containing chemicals to said container;

(d) discontinuing said conveyance of water and water containing chemicals to said container when all the chemicals within said container has been removed; and

(e) mixing said chemicals within said dialysate tank until a uniform chemical concentration is achieved.

20. The process of claim 19 wherein said water from said dialysis solution tank is sprayed downwardly onto chemicals within said container from above.

21. The process of claim 19 wherein solubilized chemicals and chemicals in a slurry with water are conveyed from said container to said dialysis solution tank by suction through a pickup wand.

22. The process of claim 19 wherein said solubilized chemicals within said dialysis solution tank are mixed by forcing said chemicals entering the tank through a toroid containing a plurality of perforations located adjacent the tank floor.

23. The process of claim 22 wherein air is introduced into the chemicals entering said tank and toroid so as to increase the mixing action within the tank.

24. The process of claim 19 wherein water is conveyed from said tank into the space above said container created by extending a plastic liner within said container over an extender that increases the effective height of said container.

25. The process of claim 19 wherein said chemicals are first conveyed into said dialysis solution tank from said container and a second container of chemicals comprising calcium salts is then conveyed into said tank.