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Thyroxine analogs and reagents for thyroid hormone assays

  • US 4,741,897 A
  • Filed: 07/08/1986
  • Issued: 05/03/1988
  • Est. Priority Date: 07/08/1986
  • Status: Expired due to Term
First Claim
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1. A compound of the formula:

  • ##STR20## wherein X is iodine or hydrogen;

    R1 is ##STR21## where n1 is an integer from 0 to about 4, n is an integer from 0 to about 5, and R4 is hydrogen, methyl, ethyl, or propyl;

    R2 is ##STR22## where n2 is an integer from about 2 to about 6, n3 is an integer from about 0 to about 2, and n4 is an integer from about 4 to about 6; and

    R3 is ##STR23## where R5 is hydrogen, CO2 R4 or --NH2 and R6 is ##STR24##

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