Dermal and transdermal patches having a discontinuous pattern adhesive layer
First Claim
1. In a dermal or transdermal drug delivery system comprising a drug occlusive backing layer, a drug reservoir thereon and a first adhesive to affix (1) said drug reservoir and occlusive backing layer to (2) a patient such that drug contained in said reservoir can be delivered by said system to said patient, and a removable drug occlusive layer on said adhesive, the improvement comprising said first adhesive being in a discrete, discontinuous pattern in a region which, when said patch is applied to said patient, constitutes a reservoir-patient contact area, said first adhesive being present in said region to a degree which results in at least 10% of said region to no more than about 60% of said region having said first adhesive thereon, such that at least 20% of the entire surface area which will contact said patient once said patch is applied to said patient has an adhesive thereon;
- said drug being insoluable in said adhesive.
1 Assignment
0 Petitions
Accused Products
Abstract
Dermal and transdermal patches having a discontinuous pattern printed adhesive layer on a first surface of an active-agent porous membrane, a non-porous backing layer in contact with a second surface of said porous membrane, opposite said first surface so as to define a compartment capable of containing an active agent or formulation thereof therein, an active-agent or formulation thereof within said compartment, and a protective overlayer on said adhesive layer distal to said porous membrane.
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Citations
28 Claims
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1. In a dermal or transdermal drug delivery system comprising a drug occlusive backing layer, a drug reservoir thereon and a first adhesive to affix (1) said drug reservoir and occlusive backing layer to (2) a patient such that drug contained in said reservoir can be delivered by said system to said patient, and a removable drug occlusive layer on said adhesive, the improvement comprising said first adhesive being in a discrete, discontinuous pattern in a region which, when said patch is applied to said patient, constitutes a reservoir-patient contact area, said first adhesive being present in said region to a degree which results in at least 10% of said region to no more than about 60% of said region having said first adhesive thereon, such that at least 20% of the entire surface area which will contact said patient once said patch is applied to said patient has an adhesive thereon;
- said drug being insoluable in said adhesive.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. In a dermal or transdermal drug delivery system comprising a drug occlusive backing layer, a drug reservoir thereon and a first adhesive to affix (1) said drug reservoir and occlusive backing layer to (2) a patient such that drug contained in said reservoir can be delivered by said system to said patient, and a removable drug occlusive layer on said adhesive, the improvement comprising said first adhesive being in a discrete, discontinuous pattern in a region which, when said patch is applied to said patient, constitutes a reservoir-patient contact area, said first adhesive being present in said region to a degree which results in at least 10% of said region to no more than about 60% of said region having said first adhesive thereon, such that at least 20% of the entire surface area which will contact said patient once said patch is applied to said patient has an adhesive thereon;
- said drug being soluable in said adhesive.
- View Dependent Claims (16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28)
Specification