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Ruthenium complexes useful as carriers for immunologically active materials

  • US 4,745,076 A
  • Filed: 09/09/1985
  • Issued: 05/17/1988
  • Est. Priority Date: 09/17/1984
  • Status: Expired due to Fees
First Claim
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1. Ruthenium complexes to which are coupled an immunologically active material, whereby the ruthenium complexes have the general formula


  • space="preserve" listing-type="equation">R.sup.2+ L.sub.1 L.sub.2 L.sub.3 I
wherein L1 and L2 are the same or different and are bathophenanthroline or benzobathphenanthroline groups substituted with sulphonic acid groups as groups conferring water-solubility, and wherein L3 is a member of the group consisting of a bathophenanthroline group and a benzobathophenanthroline group, both of which are substituted with an alkylene group having a maximum of eight carbon atoms which is terminally substituted with a --COOH, --NH2 --NCS, --I or --SO2 Hal group.

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