Process for manufacture of plastic resinous tubes

• US 4,752,426 A
• Filed: 06/27/1986
• Issued: 06/21/1988
• Est. Priority Date: 06/27/1985
• Status: Expired due to Fees

• Current Assignee: JMS Company Limited
• Original Assignee: Medical Supply Depot, Yoshito Ikada
• Inventors: Cho, Tsuneo
• Primary Examiner(s): Thurlow, Jeffery
• Assistant Examiner(s): Tentoni, Leo B.
• Application Number:
  US06/879,432
• Time in Patent Office: 725 Days
• Field of Search: 264/22, 264/81, 264/83, 264/265, 264/306, 264/347, 204/165, 204/168, 427/38, 427/45.1, 522/126, 522/134, 522/151, 522/153
• US Class Current: 264/483
• CPC Class Codes: A61M 19/00 Local anaesthesia syringes therefor A61M5/00; Hypothermia A61M5/42 takes precedence; cooling blood in a bypass of the arterial system A61M1/36
• CPC Class Codes: A61M 39/08 Tubes; Storage means specially adapted therefor
• CPC Class Codes: B29C 59/142 of profiled articles, e.g. hollow or tubular articles
• CPC Class Codes: H01J 2237/338 Changing chemical properties of treated surfaces
• CPC Class Codes: H01J 37/32192 Microwave generated discharge H01J37/32357, H01J37/32366, H01J37/32394, H01J37/32403 take precedence
• CPC Class Codes: H01J 37/32357 Generation remote from the workpiece, e.g. down-stream

Abstract

Plastic resinous tubes, particularly for medical use is improved in blood compatibility when brought into contact with blood, by applying a low-temperature plasma treatment to inner surfaces of the tubes, which plasma is produced through electrodeless electric discharges by the effect of microwave to make it possible to prevent the tube from being heated in such a treatment. The inner surfaces of the tubes thus activated may be further subjected to an inner surface graft copolymerization treatment to enhance blood compatibility.

Claims

1. A process for manufacture of bio-compatible plastic resinous tubes for medical use, comprising the steps of:

producing low-temperature plasma in a plasma chamber through electrodeless electric discharges caused by microwave;

introducing the plasma thus generated into plastic resinous tubes disposed in a position spaced apart from the plasma chamber to activate the inner surfaces of said plastic resinous tubes; and

introducing radical-polymerizable monomers into said plastic resinous tubes to graft-polymerize said monomers into polymers in the inner surfaces of said plastic resinous tubes having been activated by said plasma.

2. The process for manufacture of bio-compatible plastic resinous tubes as set forth in claim 1, wherein:

said radical-polymerizable monomers are monomers which are polymerized into water-soluble monomers when polymerized homogeneously; and

said radical-polymerizable monomers being one or more compound selected from the group consisting of acrylamide, dimethyl acrylamide, methacrylamide and vinylpyrrolidone.