Vascular catheter

• US 4,754,752 A
• Filed: 07/27/1987
• Issued: 07/05/1988
• Est. Priority Date: 07/28/1986
• Status: Expired due to Term

• Current Assignee: Trimedyne Incorporated (InnovaQuartz, LLC)
• Original Assignee: David F. Profitt, Robert Ginsburg
• Inventors: Profitt, David F., Ginsburg, Robert
• Primary Examiner(s): Rosenbaum, C. Fred
• Assistant Examiner(s): Kartchner, Gene B.
• Application Number:
  US07/079,076
• Time in Patent Office: 344 Days
• Field of Search: 128/303.12, 128/344, 128/401, 128/6, 604/113-114
• US Class Current: 606/27
• CPC Class Codes: A61B 18/08 by means of electrically-heated probes
• CPC Class Codes: A61B 18/082 Probes or electrodes therefor
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/28 for heating a thermal probe or absorber
• CPC Class Codes: A61B 2017/00084 Temperature
• CPC Class Codes: A61B 2017/22002 preventing restenosis
• CPC Class Codes: A61B 2017/22062 to be filled with liquid
• CPC Class Codes: A61B 2018/00166 Multiple lumina
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61M 2205/36 related to heating or cooling
• CPC Class Codes: A61M 25/007 Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
• CPC Class Codes: A61M 25/10 Balloon catheters A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02; inflatable balloons for placing stents or stent-grafts A61F2/958 ; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00
• CPC Class Codes: A61M 25/104 used for angioplasty

Abstract

An improved balloon-tipped catheter includes means for convectively heating the inflation medium within the balloon during dilation. In the preferred embodiment, the convective heat is provided by a radiant heating block which is attached to a laser light source through an optical waveguide extending the length of the catheter. The convectively heated balloon promotes restoration and healing of the arterial wall in the region of stenosis, which region normally suffers from cracking, tearing, and stretching. It has been found that damage to the arterial wall can sometimes result in abrupt closure of the artery and frequent restenosis in the same region.

Claims

1. A catheter comprising:

a flexible tube having distal and proximal ends, the distal end being insertable into a blood vessel;

an inflatable balloon secured to the tube near its distal end;

means for inflating the balloon to provide a volume of inflation medium therein; and

means for convectively heating the inflation medium in the balloon to a temperature in the range from about 40°

C. to 80°

C. above normal body temperature.

2. A catheter as in claim 1, wherein the means for convectively heating the volume includes a heat radiating block located inside the balloon, and means for heating the block.

3. A catheter as in claim 2, wherein the means for heating the block is a fiber optic waveguide connectable to a laser radiation source, said fiber optic waveguide being disposed to direct said radiation at said block.

4. A catheter as in claim 1, further comprising means located at the distal end of the tube for injecting a plurality of perfusate streams, wherein at least some of said perfusate streams are oblique to the axis of the tube.

5. A catheter comprising:

a flexible tube having distal and proximal ends and at least two isolated lumens extending from the distal end to the proximal end, wherein the distal end is insertable into a blood vessel;

an inflatable balloon secured to the tube near its distal end, said balloon being arranged to receive an inflation medium from one of said lumens to provide a volume of inflation medium within the balloon;

a heat radiating block secured to the tube within the inflatable balloon;

a laser radiation source; and

a fiber optic waveguide connected to said laser radiation source and disposed to direct radiation at the block in order to convectively heat the inflation medium inside the balloon.

6. A catheter as in claim 5, wherein the fiber optic waveguide is inserted through a third lumen extending through the tube from its proximal end to a location adjacent the heat radiating block.

7. A catheter as in claim 5, wherein the heat radiating block is a finned cylinder having a hollow axial passage, wherein the hollow passage is aligned with a first lumen in the tube.

8. A catheter as in claim 7, further comprising means located at the distal end of the tube for injecting a plurality of perfusate streams, where at least some of the perfusate streams are oblique to the axis of the tube.

9. A catheter as in claim 8, wherein the means for injecting is defined by a plurality of oblique ports passing through the wall of the tube from the first lumen to the exterior, said ports being located on the distal side of the heating block so that perfusate may be passed through the first lumen and the hollow passage to said ports.

10. A method for dilating an obstructed blood vessel, said method comprising:

inserting a balloon catheter into the blood vessel so that the balloon is proxiamte the obstruction;

inflating the balloon to dialate the obstruction, wherein the dilation may also tear the endothelium from the intima of the blood vessel;

convectively heating a volume of inflation medium within the balloon to a temperature in the range from about 40°

C. to 80°

C. above normal body temperature.

11. A method as in claim 10, wherein the volume is heated by directing laser light at a metal block disposed within the balloon.

12. A method as in claim 11, wherein the volume is heated for a time period in the range from about 30 to 45 seconds.

13. A method as in claim 10, wherein the blood vessel is the coronary artery.

14. A method as in claim 13, wherein the blood vessel is a peripheral artery.