Automated mean arterial blood pressure monitor with data enhancement

• US 4,754,761 A
• Filed: 10/27/1986
• Issued: 07/05/1988
• Est. Priority Date: 07/05/1985
• Status: Expired due to Term

• Current Assignee: Critikon Co. LLC (GE Aerospace)
• Original Assignee: Critikon, Inc. (Johnson & Johnson)
• Inventors: Medero, Richard, Hood, Rush W. Jr., Ramsey, Maynard III
• Primary Examiner(s): Cohen, Lee S.
• Assistant Examiner(s): SHAY, DAVID M
• Application Number:
  US06/923,231
• Time in Patent Office: 617 Days
• Field of Search: 128/677-683, 128/672, 128/685
• US Class Current: 600/496
• CPC Class Codes: A61B 5/02116 of pulse wave amplitude A61B5/02225 takes precedence
• CPC Class Codes: A61B 5/022 by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
• CPC Class Codes: A61B 5/02225 using the oscillometric method

Abstract

A blood pressure cuff is applied about a subject'"'"'s artery, and inflated above the systolic level thus fully occluding the artery for a full heart cycle. The cuff pressure is thereafter reduced to permit an increasing flow through the progressively less occluded artery, and a measure of the peak amplitudes of the successively encountered blood flow (oscillatory complex) pulses stored in memory. Also retained is the cuff pressure obtaining for each stored complex peak. In accordance with varying aspects of the present invention, the stored complex peak-representing data ensemble is corrected for aberrations; and improved data processing operates on the stored (and advantageously corrected) pulse peak data and the corresponding cuff pressure information to determine the subject'"'"'s mean arterial blood pressure.

Claims

1. In combination in digital processor controlled automated blood pressure measuring apparatus operative in conjunction with a stored program:

(a) an inflatable cuff;

(b) means for inflating and deflating said cuff;

(c) pressure transducer means coupled to said cuff for signalling the pressure existing in said cuff;

(d) means responsive to the pressure signalled by said transducer for generating a signal representing blood pressure oscillation complexes sensed by said cuff and said transducer coupled thereto;

(e) complex peak storing means for storing values characterizing the peak amplitudes of said detected oscillation complexes at different cuff pressures;

(f) cuff pressure storing means for storing the cuff pressures existing when said complex peak amplitudes arose; and

(g) mean arterial pressure determining means, said mean arterial pressure determining means comprising

(i) means for locating the maximum complex peak amplitude stored in said complex peak storing means;

(ii) means for locating a successor complex peak amplitude value stored in said complex peak storing means, said successor being the one next occurring after said maximum complex peak amplitude arose;

(iii) means, responsive to the value of said successor complex peak for selecting plural ones of the complex peak amplitudes which were generated at cuff pressures higher than that existing when said maximum complex peak arose; and

(iv) determining means for determining mean arterial pressure from

1said selected plural ones of the complex peak amplitudes,

2 the cuff pressures stored in said cuff pressure storing means corresponding to said selected plural ones, and

3 the cuff pressure which corresponds to said successor complex peak amplitude.

2. A combination as in claim 1, wherein said determining means comprises means for interpolating plural of the complex peak amplitudes and the cuff pressures corresponding thereto.

3. A combination as in claim 1, wherein said determining means comprises means for computing a weighted average of the cuff pressure stored in said cuff pressure storing means corresponding to said successor complex peak signal and a function of the cuff pressures stored in said cuff pressure storing means corresponding to said selected plural complex peak value.

4. A combination as in claim 1, and further including data purifying means, operative upon the complex peak amplitudes stored in said complex peak storing means, for correcting data inaccuracies prior to operation of said mean arterial pressure determining means.

5. A combination as in claim 4, wherein a preselected character is stored in said complex peak storing means to signal an unsuccessful pulse flow peak measurement, and wherein said data purifying means comprises means for examining the contents of said complex peak storing means and said means for examining being responsive to detecting said preselected character for replacing said character with a function of plural stored complex peak values at least one of which was obtained at a cuff pressure higher than that associated with the preselected character.

6. A combination as in claim 4, wherein a preselected character is stored in said complex peak storing means to signal an unsuccessful pulse flow peak measurement, and wherein said data purifying means comprises means for examining the contents of said complex peak storing means and responsive to detecting said preselected character for replacing said character with a measure of plural stored complex peak values at least one of said stored values having been obtained by the average of the cuff pressures next higher and next lower than that associated with the preselected character.

7. A combination as in claim 4, wherein said data purifying means includes means for searching said complex storing means for the occurrence of two equal peak amplitude values arising at successive cuff deflation pressures, and means responsive to said searching means for replacing one of the two stored equal values with a function of two other values stored in said complex peak storing means.

8. A combination as in claim 4, wherein said data purifying means includes means for searching said complex storing means for the occurrence of two equal peak amplitude values arising at successive cuff deflation pressures, and means responsive to said searching means for replacing one of the two stored equal values with a function of the next higher or the next lower values stored in said complex peak storing means.

9. In an automated oscillometric blood pressure monitor employing a pressurized cuff, means for controllably changing pressure to distinct cuff pressure levels in predetermined cuff pressure decrements, and means for measuring arterial pressure oscillation complexes through cuff pressure measurement, a method for measuring mean arterial pressure comprising the steps of:

(a) at each said level, detecting oscillation complexes, measuring and storing the peak of the envelope thereof, and storing the identification of each associated prevailing cuff pressure level;

(b) finding the amplitude of the largest of said peaks, and recording the prevailing cuff pressure level stored in association therewith;

(c) identifying a cuff pressure level having a peak next following and smaller than said largest of said peaks;

(d) identifying, in response to the amplitude of said peak next following, plural peaks which occured at pressures larger than the pressure of said largest of said peaks;

(e) interpolating said identified plural peaks; and

(f) developing mean arterial pressure as a predetermined weighted average of the cuff pressure corresponding to said interpolated amplitude and the cuff pressures corresponding to at least one of said largest and said next following peaks.

10. A method as described in claim 9 and further including the steps, prior to said finding step, of comparing said stored peaks with predetermined standards, and of substituting corrected peak data for those peaks which depart from said standards.