Method and apparatus for the localization of bleeding in the gastrointestinal tract

• US 4,773,430 A
• Filed: 01/06/1986
• Issued: 09/27/1988
• Est. Priority Date: 01/06/1985
• Status: Expired due to Fees

• Current Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (Hebrew University of Jerusalem)
• Original Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (Hebrew University of Jerusalem)
• Inventors: Porath, Asher
• Primary Examiner(s): HOWELL, KYLE
• Assistant Examiner(s): HOWELL, KYLE
• Application Number:
  US06/816,272
• Time in Patent Office: 995 Days
• Field of Search: 128/636, 128/637, 128/638, 128/768, 604/27, 604/28, 604/43, 604/35
• US Class Current: 600/581
• CPC Class Codes: A61B 5/02042 Determining blood loss or bleeding, e.g. during a surgical procedure
• CPC Class Codes: A61B 5/42 Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems A61B1/00, A61B5/4857, A61B5/486, A61B5/4866, A61B5/4869 take precedence

Abstract

The present invention relates to a method for the localization of bleeding in the gastrointestinal tract. More particularly, the present invention relates to a method wherein gastric or intestinal contents at different locations in the gastrointestinal tract are continuously checked for their hemoglobin contents. The invention also relates to an apparatus adapted to carry out the method of the invention.

Claims

1. A method for the localization of bleeding in the gastrointestinal tract comprising:

(a) introduction of a double lumen tube into the gastrointestinal tract of a patient,

(b) introduction of a physiological solution into the gastrointestinal tract through one of the tubes of said double-lumen tube, and simultaneous withdrawal of the physiological solution contaminated with gastric or intestinal fluid through the other tube of said double-lumen tube out of the body of the patient,

(c) continuously testing said contaminated solution for the presence of hemoglobin,

(d) changing the location of the end of said double-lumen tube in the gastrointestinal tract by a measurable distance and repeating steps (b) and (c) above,

(e) ascertaining the depth of tube penetration into the gastrointestinal tract at which the level of hemoglobin in the contaminated solution was maximal.

2. The method according to claim 1, wherein the double-lumen tube is introduced into the gastrointestinal tract through the nose or mouth.

3. The method according to claim 1, wherein the double-lumen tube is introduced into the gastrointestinal tract through the rectum and hemoglobin tests are carried out while said tube is introduced or slowly pulled out.

4. The method according to claim 1, in which the exact position of the tube within the patient'"'"'s gastrointestinal tract is determined by X-ray examination.

5. An apparatus for determining the location of bleeding in the gastrointestinal tract comprising:

(a) means for introducing and withdrawing a physiological solution into and from the gastrointestinal tract of a patient at equal flow rates, and

(b) means for continuously testing the withdrawn solution for the presence of hemoglobin;

the means of paragraphs (a) and (b) further comprising;

(i) a mixing head;

(ii) a first pump means adapted to introduce saline into the gastrointestinal tract of patient through a double lumen tube and to withdraw contaminated saline from the gastrointestinal tract into said mixing head;

(iii) a second pump means adapted to introduce reagents which react with hemoglobin to form a detectable product into said mixing head; and

(iv) a detector for detecting the chemical reaction product.

6. An apparatus according to claim 5 further comprising a recorder connected to the detector for continuous recording of the hemoglobin contents along the gastrointestinal tract.

7. An apparatus according to claim 5 further comprising an alarm system connected to the detector.

8. An apparatus according to claim 5, wherein the means for introducing and withdrawing a solution is radioopaque.

9. The apparatus of claim 7 in which the detector is a colorimeter.

10. A method for the localization of bleeding in the gastrointestinal tract, which comprises continuously sampling gastric or intestinal fluids from the tract without diminishing GI fluid volume while continuously moving a sampling means along the tract, testing the samples for hemoglobin content, and ascertaining the point in the tract where the sample having the highest hemoglobin content was taken.