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Ultrasonic imaging agent and method of preparation

  • US 4,774,958 A
  • Filed: 10/01/1987
  • Issued: 10/04/1988
  • Est. Priority Date: 12/05/1985
  • Status: Expired due to Term
First Claim
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1. The method of producing an ultrasonic imaging agent, comprising the steps of forming an aqueous protein solution, subjecting said solution to high frequency sonication while heating the solution sufficiently to denature portions of the protein, and forming a dispersion of microbubbles of relatively uniform size stabilized by the denatured protein.

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