Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport
First Claim
1. A method of facilitating percutaneous transport by overcoming the barrier function of the stratum corneum, said method comprisingablating the stratum corneum of a region of the skin of said patient using pulsed laser light of wavelength, pulse length, pulse energy, pulse number, and pulse repetition rate sufficient to ablate said corneum without significantly damaging the underlying epidermis.
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Abstract
A method of administering a therapeutic substance to a human patient, the method having the steps of ablating the stratum corneum of a region of the skin of the patient using pulsed laser light of wavelength, pulse length, pulse energy, pulse number, and pulse repetition rate sufficient to ablate the stratum corneum without significantly damaging the underlying epidermis, and applying the therapeutic substance to the region of ablation.
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Citations
8 Claims
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1. A method of facilitating percutaneous transport by overcoming the barrier function of the stratum corneum, said method comprising
ablating the stratum corneum of a region of the skin of said patient using pulsed laser light of wavelength, pulse length, pulse energy, pulse number, and pulse repetition rate sufficient to ablate said corneum without significantly damaging the underlying epidermis.
Specification