Multilayer analytical element and method of making, using ultrasonic or laser energy
First Claim
1. A method of making a multilayer analytical test element comprising a plurality of layers containing a single reagent layer which detects a ligand in, or detects the ligand binding capacity of, a liquid sample, and at least one of said layers is a fusible layer, which method comprisesarranging said layers in an unadhered assembly with one layer on top of the other to form a composite blank of said layers, andsubjecting said composite blank of said layers to ultrasonic or laser energy to simultaneously bond together the layers at each respective edge thereof while cutting said element from said composite blank of layers such that the fusible layer partially migrates into the reagent layer where the layers are bonded.
2 Assignments
0 Petitions
Accused Products
Abstract
A method of making a multilayer analytical test element comprises providing layers at least one of which is responsive to detect a ligand in a liquid sample, or to detect the ligand binding capacity of the sample, and at least one other layer that is fusible when subjected to sonic energy, arranging the layers one on top of the other together to form a composite blank of layers, subjecting the composite to ultrasonic or laser energy to cut the composite to the desired dimension of the test element and to simultaneously weld the layers at the edges thereof, said energy softening and fusing the fusible layer to thereby bond the layers together.
129 Citations
3 Claims
-
1. A method of making a multilayer analytical test element comprising a plurality of layers containing a single reagent layer which detects a ligand in, or detects the ligand binding capacity of, a liquid sample, and at least one of said layers is a fusible layer, which method comprises
arranging said layers in an unadhered assembly with one layer on top of the other to form a composite blank of said layers, and subjecting said composite blank of said layers to ultrasonic or laser energy to simultaneously bond together the layers at each respective edge thereof while cutting said element from said composite blank of layers such that the fusible layer partially migrates into the reagent layer where the layers are bonded.
Specification