Process and apparatus for determining female ovulation time by measurement of saliva viscoelasticity

• US 4,779,627 A
• Filed: 04/04/1986
• Issued: 10/25/1988
• Est. Priority Date: 04/04/1986
• Status: Expired due to Term

• Current Assignee: Harold J. Kosasky
• Original Assignee: Academy of Applied Science
• Inventors: Kosasky, Harold J.
• Primary Examiner(s): Coven, Edward M.
• Assistant Examiner(s): SHAY, RANDY CITRIN
• Application Number:
  US06/849,162
• Time in Patent Office: 935 Days
• Field of Search: 128/630, 128/738, 128/760, 73/54, 73/60
• US Class Current: 600/551
• CPC Class Codes: A61B 2010/0022 based on measurement of viscosity or visco-elasticity
• CPC Class Codes: G01N 11/00 Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
• CPC Class Codes: G01N 33/487 of liquid biological material

Abstract

Viscoelastic measurements of sublingual saliva thinning minimums are employed reliably to determine the approach of ovulation in females and other related hormonal and rheological functions.

Claims

1. A process for determining the time of ovulation of a female, that comprises, extracting a sample of sublingual saliva from the mouth of the female;

compressing the sample between opposing surfaces adapted to cause adherence of the saliva to the same;

applying a predetermined relative force between said surfaces to stretch the saliva, the amount of stretching of the saliva providing a measure of the degree of viscoelasticity of the saliva under such predetermined force; and

providing an indication if there is near and substantial coincidence of the measured degree of viscoelasticity with a predetermined unique monthly minimum dip of viscoelasticity in the sublingual saliva of the female to identify that the time of midcycle of ovulation is about to occur.

2. A process as claimed in claim 1 and in which the saliva of the female is observed to determine said minimum dip of viscoelasticity and said predetermined force is adjusted to cause fracture of the sample when the viscoelasticity decreases in said dip.

3. A process as claimed in claim 2 and in which said force is calibrated to provide up to 48 hours of indication for purposes of determining optimum fertility.

4. A process as claimed in claim 1 and in which the sample is of the order of 0.25 mm in thickness.

5. Ovulation indicating apparatus having, in combination, plunger means provided with a finely roughened end surface insertable in the mouth to coat the surface with an adhering sublingual saliva sample;

means comprising a re-entrant tube disposed within a coaxial cylinder for receiving the plunger means, said receiving means having an opposing roughened bottom surface against which the sample carried by the plunger means end surface is to be compressed; and

means comprising a calibrated weight carried by said tube for applying a force between the roughened surfaces to stretch the compressed saliva sample, the force-applying means being calibrated to produce a predetermined force equal to that required to cause fracture of the sample and separation of said plunger means and said tube when the viscoelasticity of the sample substantially coincides with a predetermined unique monthly minimum dip in sublingual saliva viscoelasticity, said cylinder having means operating as a result of the separation of said plunger means and said tube for indicating such fracture of the sample to enable intercourse abstinence or activity.

6. An ovulation indicating apparatus as claimed in claim 5 and in which said indicating means includes an indicator and means disposed near a bottom of the cylinder for activating the indicator upon dropping of the tube within the cylinder.

7. A process for determining the time of ovulation of a female, comprising the steps of extracting a sample of sublingual saliva from the mouth of the female;

compressing the sample between a pair of opposed surfaces conditioned to cause adherence of the saliva to the surfaces;

stretching the sample between the two surfaces with a predetermined force, the amount of stretch in response to said predetermined force providing a measure of viscoelasticity of the sample; and

ascertaining whether the measure of viscoelasticity substantially coincides with a predetermined unique monthly minimum dip of viscoelasticity in the sublingual saliva of the female.

8. A process as claimed in claim 7 and in which the substantial coincidence of the measure of viscoelasticity with the predetermined monthly minimum dip is ascertained by providing an observable indication of such coincidence.

9. A process as claimed in claim 8 and in which said indication is visibly observable.

10. A process as claimed in claim 8 and in which said indication is provided as a result of separation of said two surfaces.