Method and apparatus for supplying concentrate for use in medical treatments

• US 4,783,273 A
• Filed: 12/17/1987
• Issued: 11/08/1988
• Est. Priority Date: 01/29/1987
• Status: Expired due to Fees

• Current Assignee: Gambro AB BO
• Original Assignee: Gambro AB (Baxter International Inc.)
• Inventors: Shaldon, Stanley, Knutsson, Stefan L.
• Primary Examiner(s): Sever, Frank
• Application Number:
  US07/133,995
• Time in Patent Office: 327 Days
• Field of Search: 210/644-648, 210/649-652, 210/791, 210/797, 210/798, 210/106, 210/108, 210/194, 210/195.1, 210/195.2, 210/258, 210/257.2, 210/321.1, 210/321.2 , 210/321.3, 210/333.01, 210/409, 210/411, 210/416.1, 210/425, 210/427, 210/433.2
• US Class Current: 210/798
• CPC Class Codes: A61M 1/1656 Apparatus for preparing dialysates
• CPC Class Codes: A61M 1/1672 using membrane filters, e.g. for sterilising the dialysate
• CPC Class Codes: A61M 1/169 using chemical substances
• CPC Class Codes: A61M 1/3462 Circuits for the preparation thereof

Abstract

Apparatus for the supply of concentrate for use in medical treatment processes is disclosed, including a concentrate filter including a membrane, an inlet conduit for supplying concentrate to the inlet side of the concentrate filter during normal use and for supplying cleaning fluid to the inlet side of the concentrate filter during cleaning, an outlet conduit for withdrawing the filtered concentrate or a portion of the cleaning fluid from the outlet side of the concentrate filter, and a cleaning fluid withdrawal conduit connected to the inlet side of the concentrate filter and including a valve so that it can be closed during normal use of the concentrate filter and opened during cleaning of the concentrate filter in order to flush a portion of the cleaning fluid through the concentrate filter. Methods for supplying concentrate to be used for medical treatment purposes are also disclosed.

Claims

1. Apparatus for the supply of concentrate to be used for medical treatment purposes comprising means for enabling substantially easy sterilization and/or disinfection of low percolation filters when and/or where said concentrate favors bacterial growth, including, a concentrate filter, said concentrate filter including an inlet side and an outlet side separated by membrane means, inlet conduit means for supplying said concentrate to said inlet side of said concentrate filter during normal use of said concentrate filter and for supplying a cleaning fluid to said inlet side of said concentrate filter during cleaning of said concentrate filter, outlet conduit means for withdrawing said filtered concentrate from said outlet side of said concentrate filter during normal use of said concentrate filter and for withdrawing a first portion of said cleaning fluid from said outlet said of said concentrate filter during cleaning of said concentrate filter, and cleaning fluid withdrawal means connected to said inlet side of said concentrate filter, said cleaning fluid withdrawal means including valve means selected to enable said cleaning fluid withdrawal means to be closed during normal use of said concentrate filter and opened in order to flush a second portion of cleaning fluid through said concentrate filter during cleaning of said concentrate filter.

2. The apparatus of claim 1 including drain means for disposal of said second portion of said cleaning fluid passing through said cleaning fluid withdrawal means.

3. The apparatus of claim 1 wherein said cleaning fluid withdrawal means includes pressure control valve means for controlling the pressure within said cleaning fluid withdrawal means.

4. The apparatus of claim 1 wherein said cleaning fluid withdrawal means includes pressure control valve means for controlling the pressure within said cleaning fluid withdrawal means.

5. The apparatus of claim 1 wherein said outlet conduit means includes suction pump means for withdrawing said filtered concentrate from said outlet side of said concentrate filter during normal use of said concentrate filter and for withdrawing said cleaning fluid from said outlet side of said concentrate filter during cleaning of said concentrate filter.

6. The apparatus of claim 5 including first concentrate supply means for supplying said concentrate to said inlet conduit means during normal use of said concentrate filter, medical treatment conduit means for supplying said filtered concentrate withdrawn from said outlet side of said concentrate filter for said medical treatment purposes during normal use of said concentrate filter and for carrying said first portion of said cleaning fluid withdrawn from said outlet side of said concentrate filter during cleaning of said concentrate filter, additional concentrate supply means for supplying additional concentrate to be used for said medical treatment purposes, said additional concentrate supply means including additional concentrate conduit means for supplying said additional concentrate to said medical treatment conduit means, said suction pump means in said outlet conduit means comprising a first suction pump means, and including a second suction pump means in said additional concentrate supply means for supplying said additional concentrate to said medical treatment conduit means during normal use of said concentrate filter, disconnect means for disconnecting said first and second concentrate supply means from said inlet conduit means and said additional concentrate conduit means, respectively, and common cleaning fluid supply means for supplying said cleaning fluid to said inlet conduit means and said additional concentrate conduit means whereby said cleaning fluid can be supplied both to said inlet side of said concentrate filter and to said additional concentrate conduit means during cleaning of said concentrate filter.

7. The apparatus of claim 5 including branch outlet conduit means connected to said outlet conduit means for withdrawing at least a portion of said first portion of said cleaning fluid withdrawn from said outlet side of said concentrate filter during cleaning of said concentrate filter, said branch outlet conduit means including drain means for disposal of said at least a portion of said first portion of said cleaning fluid.

8. The apparatus of claim 7 wherein said branch outlet conduit means is located between said concentrate filter and said suction pump means.

9. The apparatus of claim 7 wherein said branch outlet conduit means includes pressure control valve means for controlling the pressure within said branch outlet conduit means.

10. The apparatus of claim 7 wherein said cleaning fluid withdrawal means includes first pressure control valve means for controlling the pressure within said cleaning fluid withdrawal means, and wherein said branch outlet conduit means includes second pressure control valve means for controlling the pressure within said branch outlet conduit means.

11. The apparatus of claim 10 wherein said first pressure control valve means is set at a higher pressure than said second pressure control valve means.

12. The apparatus of claim 1 including a water filter, said water filter including an inlet side and an outlet side separated by membrane means, water inlet conduit means for supplying said water to said inlet side of said water filter during normal use of said water filter and for supplying cleaning fluid to said inlet side of said water filter during cleaning of said water filter, water outlet conduit means for withdrawing said filtered water from said outlet side of said water filter during normal use of said water filter and for withdrawing at least a portion of said cleaning fluid from said outlet side of said water filter during cleaning of said water filter, unfiltered cleaning fluid withdrawal means connected to said inlet side of said water filter, said unfiltered cleaning filter withdrawal means including valve means whereby said unfiltered cleaning fluid withdrawal means may be closed during normal use of said water filter and opened in order to flush a second portion of said cleaning fluid through said water filter during cleaning of said water filter, and water fluid connection means for connecting said water outlet conduit means to said inlet conduit means for supplying said cleaning fluid to said inlet side of said concentrate filter during cleaning of said concentrate filter.

13. The apparatus of claim 12 including supply duct means connected to said water inlet conduit means for supplying cleaning fluid to said water inlet conduit means during cleaning of said water filter.

14. The apparatus of claim 13 wherein said water outlet conduit means includes shut-off valve means.

15. The apparatus of claim 14 wherein said shut-off valve means is located between said water filter and said concentrate filter.

16. A method for supplying concentrate to be used for medical treatment purposes comprising enabling easy sterilization and/or disinfection of low percolation filters when and/or where aid concentrate favors bacterial growth, by, supplying said concentrate to the inlet side of a concentrate filter, withdrawing said filtered concentrate from the outlet side of said concentrate filter, intermittently terminating the supply of said concentrate to said inlet side of said concentrate filter and supplying cleaning fluid to said inlet side of said concentrate filter so as to clean said concentrate filter, withdrawing a first portion of said cleaning fluid from said outlet side of said concentrate filter, and withdrawing a second portion of said cleaning fluid from said inlet side of said concentrate filter so as to simultaneously flush said inlet side and said outlet side of said concentrate filter with said cleaning fluid during said cleaning of said concentrate filter.

17. The method of claim 16 including disposing of said second portion of said cleaning fluid withdrawn from said inlet side of said concentrate filter.

18. The method of claim 16 including controlling the pressure of said second portion of said cleaning fluid withdrawn from said inlet side of said concentrate filter.

19. The method of claim 16 including pumping said filtered concentrate withdrawn from said outlet side of said concentrate filter, and pumping said first portion of said cleaning fluid intermittently withdrawn from said outlet side of said concentrate filter.

20. The method of claim 16 wherein said concentrate supplied to said inlet side of said concentrate filter comprises a first concentrate portion, and including supplying said filtered first concentrate portion withdrawn from said outlet side of said concentrate filter to a primary supply conduit for said medical treatment process, supplying a second concentrate portion to said primary supply conduit, pumping said filtered first concentrate portion to said primary supply conduit, pumping said second concentrate portion to said primary supply conduit, and intermittently disconnecting said supply of said first and said second concentrate portions and supplying said cleaning fluid to both said inlet side of said concentrate filter and said primary supply conduit during cleaning of said concentrate filter.

21. The method of claim 16 including withdrawing at least a portion of said first portion of said cleaning fluid withdrawn from said outlet side of said concentrate filter, and disposing of said at least a portion of said first portion of said cleaning fluid.

22. The method of claim 21 including controlling the pressure in said at least a portion of said first portion of said cleaning fluid withdrawn from said outlet side of said concentrate filter.

23. The method of claim 21 including controlling the pressure in said at least a portion of said first portion of said cleaning fluid withdrawn from said outlet side of said concentrate filter and controlling the pressure in said second portion of said cleaning fluid withdrawn from said inlet side of said concentrate filter.

24. The method of claim 23 including controlling said pressure of said at least a portion of said first portion of said cleaning fluid to a higher pressure than said second portion of said cleaning fluid.

25. The method of claim 16 including supplying water to the inlet side of a water filter, withdrawing said filtered water from the outlet side of said water filter, intermittently supplying cleaning fluid to said inlet side of said water filter so as to clean said water filter, withdrawing a first portion of said cleaning fluid from said outlet side of said water filter, and withdrawing a second portion of said cleaning fluid from said inlet side of said water filter, so as to simultaneously flush said inlet side and said outlet side of said water filter with said cleaning fluid during said cleaning of said water filter, supplying said filtered water withdrawn from said outlet side of said water filter to said primary supply conduit for said medical treatment process, and intermittently supplying at least a portion of said cleaning fluid withdrawn from said outlet side of said water filter to said inlet side of said concentrate filter so as to clean said concentrate filter.