Device for determining depth of anaesthesia

• US 4,788,982 A
• Filed: 01/13/1987
• Issued: 12/06/1988
• Est. Priority Date: 01/23/1986
• Status: Expired due to Fees

• Current Assignee: ICOR AB (Teleflex Incorporated)
• Original Assignee: ICOR AB (Teleflex Incorporated)
• Inventors: Lindblad, Lars-Erik, Gedeon, Andras
• Primary Examiner(s): Howell, Kyle L.
• Assistant Examiner(s): Sykes, Angela D.
• Application Number:
  US07/003,035
• Time in Patent Office: 693 Days
• Field of Search: 128/670-671, 128/672, 128/700, 128/696, 128/687, 128/706, 128/664-667
• US Class Current: 600/483
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/1106 to assess neuromuscular blockade, e.g. to estimate depth of anaesthesia
• CPC Class Codes: A61B 5/364 Detecting abnormal ECG interval, e.g. extrasystoles, ectopic heartbeats
• CPC Class Codes: A61B 5/4821 Determining level or depth of anaesthesia A61B5/1106 takes precedence

Abstract

A device for determining the depth of anaesthesia of a patient, the device including an optical measuring means (1) for measuring on a part (2) of the patient an optical parameter such as transmission or reflection, which is influenced by the circulation of the blood through this part of the patient'"'"'s body, and to produce an electric signal which varies in accord with this parameter. This signal is related to the periodic variations in the blood-pressure of the patient and thus has a frequency which coincides with the heart frequency of the patient and a maximum amplitude and a minimum amplitude which are related respectively to the systolic and diastolic blood-pressure of the patient. The signal is applied to signal processing circuits (3) which determine the variation in the period of the signal (Δ(R-R)) and the variation in its maximum amplitude (ΔP_max) or minimum amplitude (ΔP_min) or in the difference between its maximum and minimum amplitudes (Δ(P_max -P_min)) and construct a magnitude (K) which is proportional to the variation in the period of the signal or is preferably proportional to the ratio between the variation in the period of the signal and the variation in the maximum amplitude or minimum amplitude of the signal or in the difference between the maximum and minimum amplitudes. This magnitude (K) is presented as a measurement of the depth to which the patient has been anesthetized.

Claims

1. A device for determining the depth of anaesthesia of a patient, comprising:

a measuring means for measuring, on a part of the patient'"'"'s body, a periodically varying optical parameter of blood circulating through said part, said optical parameter having a frequency corresponding to the R-R interval of said patient and said optical parameter having an amplitude corresponding to the blood pressure of the patient, said measuring means including means for generating an electric signal which varies in accord with this parameter;

signal processing circuit means for receiving said signal generated by said measuring means, said circuit means including means for deriving from said signal a first value representative of variation in the length of successive R-R intervals, as well as means for deriving from said signal a second value representative of variation in the amplitude of said electric signal at a given point during each of said successive intervals, said circuit means also including means for obtaining a ratio of said first and second values;

whereby said ratio is taken as a measurement of the depth to which the patient is anesthetized.

2. A device as claimed in claim 1, wherein said second value is respresentative of the variation in the maximum amplitude of said electric signal during said successive R-R intervals.

3. A device as claimed in claim 1, wherein said second value is representative of the variation in the minimum amplitude of said electric signal during successive R-R intervals.

4. A device as claimed in claim 1, wherein said first and second values are determined within a frequency range of between 0 to 0.5 Hz.

5. A device as claimed in claim 1, wherein said first and second values are proportional to said variation in the length of successive R-R intervals and to said variation in the amplitude of said electric signal, respectively.

6. A device as claimed in claim 1, wherein said second value is representation of the variation in the difference between the maximum and minimum amplitudes of said electric signal during successive R-R intervals.