Immunoelectrophoresis method for diagnosing and differentiating cancer using lectins
First Claim
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1. A method of differentiating primary hepatic carcinoma from metastatic hepatic carcinoma, comprising obtaining a sample of a body fluid from a patient suspected of having hepatic carcinoma, assaying said sample by means of cross-immunoaffinoelectrophoresis on each one of a pair of lectins selected from the group consisting of ConA-LCH, ConA-PHA-E, RCA-I-LCH, RCA-I-BSA-II and BSA-II-LCH, for the presence of α
- -fetoprotein specific fraction binding patterns; and
differentiating primary hepatic carcinoma from metastatic hepatic carcinoma based on the resulting specific fraction binding patterns.
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Abstract
Disclosed is a method for diagnosing and differentiating cancer by qualitative and quantitative determination according to an immuno-serological assay of cancer-related antigens in a body fluid, particularly glycoprotein, glycolipid and glycoantigen produced by cancerization or dedifferentiation of normal cells.
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4 Claims
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1. A method of differentiating primary hepatic carcinoma from metastatic hepatic carcinoma, comprising obtaining a sample of a body fluid from a patient suspected of having hepatic carcinoma, assaying said sample by means of cross-immunoaffinoelectrophoresis on each one of a pair of lectins selected from the group consisting of ConA-LCH, ConA-PHA-E, RCA-I-LCH, RCA-I-BSA-II and BSA-II-LCH, for the presence of α
- -fetoprotein specific fraction binding patterns; and
differentiating primary hepatic carcinoma from metastatic hepatic carcinoma based on the resulting specific fraction binding patterns. - View Dependent Claims (2)
- -fetoprotein specific fraction binding patterns; and
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3. A method of differentiating oophoroma from metastatic hepatic carcinoma, comprising obtaining a sample of a body fluid from a patient suspected of having oophoroma or metastatic hepatic carcinoma, assaying said sample by means of crossed-immunoaffinoelectrophoresis on each one of a pair of lectins selected form the group consisting of PHA-E-RCA-I and PHA-E-BSA-II, for the presence of α
- -fetoprotein specific fraction binding patterns; and
differentiating oophoroma from metastatic hepatic carcinoma based on the resulting specific fraction binding patterns. - View Dependent Claims (4)
- -fetoprotein specific fraction binding patterns; and
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