Method of controlling laser energy removal of plaque to prevent vessel wall damage

• US 4,791,926 A
• Filed: 11/10/1987
• Issued: 12/20/1988
• Est. Priority Date: 11/10/1987
• Status: Expired due to Term

• Current Assignee: Edwards Lifesciences Corporation
• Original Assignee: Baxter Travenol Laboratories Incorporated
• Inventors: Fry, Stephen M.
• Primary Examiner(s): HINDENBURG, MAX F
• Application Number:
  US07/119,167
• Time in Patent Office: 406 Days
• Field of Search: 128/303.1, 128/395-398, 219/121 LA, 219/121 LB
• US Class Current: 606/7
• CPC Class Codes: A61B 18/20 using laser
• CPC Class Codes: A61B 18/245 for removing obstructions in blood vessels or calculi
• CPC Class Codes: A61B 2018/00636 Sensing and controlling the application of energy

Abstract

A method of controlling laser energy removal of plaque or other obstructions from a vessel of the cardiovascular system includes advancing a laser delivery catheter to a position in proximity with a targeted lesion, placing a laser energy sensor device in a monitoring position adapted to sense laser energy from the catheter that passes beyond the lesion, and controlling the laser energy according to the output of the sensor. An intraoperative approach places the sensor external to the vessel, while a percutaneous approach places the sensor within the vessel utilizing an additional sensor fiber on the catheter that extends beyond the lesion to the monitoring position. Each fiber in a multifiber laser delivery bundle may be controlled according to sensor output for precision aiming and improved laser control.

Claims

1. A laser delivery system, comprising:

a catheter adapted to be advanced within a vessel to a position in which a distal end of the catheter is in proximity with a targeted lesion;

at least one laser delivery fiber extending within the catheter to the distal end through which to propagate laser energy toward the lesion; and

a laser energy sensor adapted to be placed in a monitoring position beyond the lesion and sense laser energy propagated through the laser delivery fibers that passes beyond the lesion;

whereby the output of the sensor can be used to control the propagation of laser energy through the fiber in order to subject the lesion to laser energy without damaging the vessel wall beyond the lesion; and

wherein the laser energy sensor includes a sensor fiber extending within the catheter and beyond the distal end to a position sufficiently beyond the distal end to extend through an opening in the lesion to the monitoring position.

2. A method of removing an obstruction from a vessel of the cardiovascular system with laser energy, comprising:

advancing a laser delivery catheter within the vessel to a position in proximity with a targeted lesion in the vessel;

placing a laser energy sensor in a monitoring position adapted to sense laser energy from the catheter that passes beyond the lesion;

propagating laser energy through the catheter toward the lesion to subject the lesion to the laser energy; and

controlling the laser energy according to the output of the sensor.

3. A method as recited in claim 2, wherein:

the sensor is placed external to the vessel.

4. A method as recited in claim 3, wherein:

the laser delivery catheter has a plurality of laser delivery fibers;

the step of advancing the laser delivery catheter includes advancing the catheter to a position in which the distal end of the laser delivery fibers are in proximity with the targeted lesion; and

the step of propagating laser energy includes propagating laser energy through selected ones of the laser delivery fibers according to the output of the sensor.

5. A method as recited in claim 4, wherein the step of propagating laser energy includes:

propagating laser energy through the laser delivery fibers in groups of one or more fibers, one group at a time.

6. A method as recited in claim 2, wherein:

the sensor is placed within the vessel.

7. A method as recited in claim 6, wherein:

the step of advancing a laser delivery catheter includes using a laser delivery catheter having a plurality of laser delivery fibers and a sensor fiber,

the step of advancing a laser delivery catheter further includes advancing the catheter to a position in which the distal end of the laser delivery fibers are in proximity with a targeted lesion and the sensor fiber extends beyond the lesion to a position adapted to sense laser energy passing beyond the lesion;

the step of propagating laser energy includes propagating laser energy through selected ones of the laser delivery fibers according to the output of the sensor.

8. A method as recited in claim 7, wherein the step of propagating laser energy includes:

propagating laser energy through the laser delivery fibers in groups of one or more fibers, one group at a time.

9. A method as recited in claim 2, wherein the step of controlling the laser energy includes:

producing a human sensible signal to alert an operator in the event more than a predetermined level of laser energy passes beyond the lesion.

10. A method as recited in claim 2, wherein the step of controlling the laser energy includes:

producing an electrical control signal to be used in controlling the laser in the event more than a predetermined level of laser energy passes beyond the lesion.

11. A method of removing an obstruction from a vessel of the cardiovascular system with a laser delivery catheter having a plurality of laser delivery fibers and a sensor fiber, comprising:

advancing the catheter to a position in which the distal end of the laser delivery fibers are in proximity with a targeted lesion and the sensor fiber extends beyond the lesion to a position adapted to sense laser energy passing beyond the lesion;

propagating laser energy through at least one of the laser delivery fibers toward the lesion;

processing the output of the sensor to produce an electrical signal to be used in controlling the laser energy according to the level of laser energy passing beyond the lesion as indicated by the output of the sensor; and

deactivating the laser energy with the electrical signal in the event more than a predetermined amount of laser energy passes beyond the lesion.

12. A method as recited in claim 11, wherein the step of processing the output of the sensor includes:

selecting a group of one or more fibers through which to propagate laser energy that is directed at a portion of the targeted lesion.

13. A method as recited in claim 11, wherein the step of processing the output of the sensor includes:

decoupling the laser energy from a fiber that is in a position to miss the lesion.

14. A laser delivery catheter, comprising:

a catheter body adapted to be advanced within a vessel to a position in which a distal end of the catheter body is in proximity with a targeted lesion;

at least one laser delivery fiber extending within the catheter body to the distal end through which to propagate laser energy toward the lesion; and

a sensor fiber extending within the catheter body and beyond the distal end to a position sufficiently beyond the distal end to extend through an opening in the lesion to a monitoring position beyond the lesion.

15. A laser delivery catheter, comprising:

a catheter body adapted to be advanced within a vessel to a position in which a distal end of the catheter body is in proximity with a targeted lesion;

at least one laser delivery fiber extending within the catheter body to the distal end through which to propagate laser energy toward the lesion; and

a sensor fiber extending within the catheter body, which sensor fiber is adapted to be selectively extended beyond the distal end to a position sufficiently beyond the distal end to extend through an opening in the lesion to a monitoring position beyond the lesion.

16. A laser delivery system, comprising:

a catheter adapted to be advanced within a vessel to a position in which a distal end of the catheter is in proximity with a targeted lesion;

at least one laser delivery fiber extending within the catheter to the distal end through which to propagate laser energy toward the lesion; and

a laser energy sensor adapted to be placed in a monitoring position beyond the lesion and sense laser energy propagated through the laser delivery fibers that passes beyond the lesion;

whereby the output of the sensor can be used to control the propagation of laser energy through the fiber in order to subject the lesion to laser energy without damaging the vessel wall beyond the lesion; and

wherein the laser energy sensor includes a sensor fiber extending within the catheter, which sensor fiber is adapted to be selectively extended beyond the distal end to a position sufficiently beyond the distal end to extend through an opening in the lesion to the monitoring position.