Device and method for chronic in-vivo measurement of internal body pressure

• US 4,796,641 A
• Filed: 07/06/1987
• Issued: 01/10/1989
• Est. Priority Date: 07/06/1987
• Status: Expired due to Term

• Current Assignee: Transoma Medical, Inc.
• Original Assignee: Data Sciences Incorporated
• Inventors: Brockway, Brian P., Mills, Perry A.
• Primary Examiner(s): Howell, Kyle L.
• Assistant Examiner(s): Sykes, Angela D.
• Application Number:
  US07/069,728
• Time in Patent Office: 554 Days
• Field of Search: 128/672.5, 128/748, 128/903, 128/DIGS. 12-13, 604/246-247, 604/266, 604/892.1
• US Class Current: 600/561
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/076 Permanent implantations telemetry using implanted circuitry A61B5/0031; implanted stimulators for therapy A61N1/3605, A61N1/362, A61N1/372
• CPC Class Codes: Y10S 128/13 Infusion monitoring
• CPC Class Codes: Y10S 128/903 Radio telemetry

Abstract

A device capable of sensing pressure allows the sensor and amplifying electronics to be packaged in a very small size and implanted within the body. The sensor consists of a small catheter, the tip of which is placed at the point at which pressure is to be measured, attached to a solid-state pressure sensor. The catheter is filled with a fluid and is connected to an implantable infusion pump which dispenses through the lumen of the catheter, heparin or other drug which inhibits thrombogenisis.

Claims

1. An inplantable device for sensing an internal body pressure of an animal, the device comprising:

implantable catheter means having proximal and distal ends, the distal end for placement at a position within the animal at which the internal body pressure is to be sensed;

implantable pressure sensing means connected to the proximal end of the catheter means for providing a signal which is a function of the internal body pressure;

implantable osmotic infusion pump means connected to the proximal end of the catheter means for supplying doses of an antithrombogenic solution to the distal end; and

means associated with the osmotic infusion pump means for preventing body fluid from entering the distal end of the catheter means.

2. The device of claim 1 wherein the means for preventing body fluid from entering the distal end includes flow restrictor means associated with the osmotic infusion pump means.

3. The device of claim 1 wherein the means for preventing body fluid from entering the distal end includes check valve means connected between the osmotic infusion pump means and the catheter means.

4. The device of claim 1 wherein the catheter means includes a coating on an outer surface at its distal end for reducing ability of thrombi to adhere to the distal end.

5. The device of claim 4 wherein the coating is a urethane material.

6. The device of claim 1 and further including:

access catheter means connected to the proximal end for providing fluid flow through the catheter means during and following implantation prior to the osmotic infusion pump means reaching a desired output flow.

7. The device of claim 1 wherein the pressure sensing means includes:

pressure transducer means connected to the proximal end for providing a transducer signal which varies as a function of the fluid pressure at the proximal end; and

transmitter means connected to the transducer means for transmitting a signal out of the animal which is a function of the transducer signal.

8. The device of claim 7 wherein the pressure sensing means further includes:

housing means for housing the pressure transducer means and the transmitter means.

9. A method of sensing an internal body pressure within a body of an animal, the method comprising:

implanting within the body of the animal a sensing catheter with a distal end of the sensing catheter positioned to be exposed to the internal body pressure;

implanting a pressure transducer within the body with a proximal end of the sensing catheter for providing a transducer signal as a function of fluid pressure at the proximal end;

implanting an osmotic infusion pump within the body and connected to the proximal end of the sensing catheter for supplying doses of an antithrombogenic solution through the sensing catheter to the distal end;

implanting a transmitter within the body and connected to the pressure transducer for transmitting a transmitter signal out of the animal which is a function of the transducer signal; and

monitoring the transmitter signal over an extended time period to provide a record of variation of the internal body pressure over time.

10. The method of claim 9 and further comprising:

connecting a check valve in a flow path between the osmotic infusion pump and the sensing catheter to prevent body fluid from entering the distal end of the catheter.

11. The method of claim 9 and further comprising:

connecting an access catheter to the proximal end of the sensing catheter with a proximal end of the access catheter being accessable from outside the body of the animal; and

providing fluid flow through the access catheter to the sensing catheter during and following implantation until the osmotic infusion pump reaches a desired output fluid flow.