Integrated drug dosage form and metering system
First Claim
1. An ingestable medicament tape, comprising:
- about 10 to 40 weight % of a physiologically acceptable thermoplastic polymer selected from the group consisting of polyvinylpyriolidone, hydroxypropylmethylcellulose, and hydroxypropycellulose;
about 15 to 50 weight % of a polysaccharide;
about 5 to 40 weight % of a compatible physiologically acceptable plasticizer; and
about 0 to 20 weight % sorbitol;
said ingestable medicament tape being capable of being fed from a roller and cut at preselected lengths to provide a predetermined medicament dosage, having a tensile strength of at least 200 psi, and containing from 0.01 to 2 mg drug/mm3.
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0 Petitions
Accused Products
Abstract
An automatic drug tape dispensing and metering device and a roll of drug tape housed in a small portable dispenser unit. The dispenser contains a measurement device for carefully measuring the length of tape as it is dispensed from the dispenser. A counter monitors the remaining doses of drug tape remaining within the dispenser. A timer device may be provided to alert the patient that it is time for the medicament to be dispensed. As the lid of the dispenser unit is opened, the measured length of drug tape is severed from the roll by a cutter blade incorporated into the lid. The device permits a physician to accurately customize the dosage and administration of the medicament to be given a patient by adjusting the tape length released for each single dose and selecting the time intervals between dosages.
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Citations
11 Claims
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1. An ingestable medicament tape, comprising:
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about 10 to 40 weight % of a physiologically acceptable thermoplastic polymer selected from the group consisting of polyvinylpyriolidone, hydroxypropylmethylcellulose, and hydroxypropycellulose; about 15 to 50 weight % of a polysaccharide; about 5 to 40 weight % of a compatible physiologically acceptable plasticizer; and about 0 to 20 weight % sorbitol; said ingestable medicament tape being capable of being fed from a roller and cut at preselected lengths to provide a predetermined medicament dosage, having a tensile strength of at least 200 psi, and containing from 0.01 to 2 mg drug/mm3. - View Dependent Claims (4, 5, 6, 7, 8)
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2. An ingestable medicament tape, comprising:
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about 10 to 20 weight % hydroxypropylcellulose; about 30 to 50 weight % starch; about 5 to 20 weight % of a physiologically compatible plasticizer; and about 7.5 to 20 weight % of sorbitol; said ingestable medicament tape being capable of being fed from a roll and cut at preselected lengths to provide a predetermined medicament dosage, having a tensile strength of at least 250 psi, and containing from 0.01 to 2 mg drug/mm3.
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3. An ingestable medicament tape, comprising:
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about 10 to 15 weight % of hydroxypropylcellulose; about 32 to 45 weight % starch; about 10 to 20 weight % triethylcitrate; and about 10 to 15 weight % sorbitol; said ingestable medicament tape capable of being fed from a roll and cut at preselected lengths to provide a predetermined medicament dosage;
having a tensile strength of at least about 300 psi, a thickness of from about 2 to about 20 mil, and a width in the range of about 0.25 to 1 cm;
containing from 0.01 to 2 mg drug/mm3 ; and
exhibiting less than about 5% dimensional change due to ambient variations in temperature and humidity. - View Dependent Claims (9, 10)
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11. A digestable medicament tape capable of being fed from a roll and cut at preselected lengths providing a predetermined medicament dosage, having a tensile strength of at least about 250 psi, a thickness of from about 2 to 12 mil, from about 0.01 to 2 mg drug/mm3 and less than about a 5% dimensional change due to ambient variations in temperature and humidity.
Specification