Support for biomedical implant device

• US 4,798,585 A
• Filed: 06/08/1987
• Issued: 01/17/1989
• Est. Priority Date: 06/06/1986
• Status: Expired due to Term

• Current Assignee: Asahi Kogaku Kogyo Kabushiki Kaisha
• Original Assignee: Asahi Kogaku Kogyo Kabushiki Kaisha
• Inventors: Minoo, Osamu, Kitaoka, Tateki, Inoue, Masahide, Nakabayashi, Nobuo, Ichitsuka, Takeshi, Takeda, Tatsumichi, Hirayama, Yasuhiko, Koshikawa, Shozo
• Primary Examiner(s): Ostrager, Allen M.
• Application Number:
  US07/059,445
• Time in Patent Office: 589 Days
• Field of Search: 604/93, 604/175, 604/185, 604/891.1
• US Class Current: 604/175
• CPC Class Codes: A61F 2310/00293 containing a phosphorus-containing compound, e.g. apatite
• CPC Class Codes: A61L 27/12 Phosphorus-containing materials, e.g. apatite
• CPC Class Codes: A61L 29/02 Inorganic materials

Abstract

A support for a biomedical implant device in which the support has a surface layer composed of a biocompatible calcium phosphate material such as sintered hydroxyapatite with a porosity of 50-60% and pore size of 0.5-500 micrometers. Preferably, the surface layer is formed with projections or recesses of a few hundred micrometers size.

Claims

1. A biomedical implant device for implantation within tissue of a body, comprising:

a support having a surface layer to be contacted with said tissue and composed of a biocompatible calcium phosphate material; and

a medically operative part at least partially enclosed by said surface layer.

2. A biomedical implant device as recited in claim 1, wherein said calcium phosphate material is sintered hydroxapatite.

3. A biomedical implant device as recited in claim 1, wherein said calcium phosphate material has a porosity of 5-60%.

4. A biomedical implant device as recited in claim 3 wherein said porosity is in a range of 20-40%.

5. A biomedical implant device as recited in claim 2, wherein said calcium phosphate material has a porosity of 5-60%.

6. A biomedical implant device as recited in claim 1, wherein said calcium phosphate material has a porosity of 5-60% and has voids with an average pore size of 0.5-500 micrometers.

7. A biomedical implant device as recited in claim 6, wherein said average pore size is 5-200 micrometers.

8. A biomedical implant device as recited in claim 2, wherein said calcium phosphate material has a porosity of 5-60% and has voids with an average pore size of 0.5-500 micrometers.

9. a biomedical implant device as recited in claim 8, wherein said average pore size is 5-200 micrometers.

10. A biomedical implant device as recited in claim 1, wherein said support further comprises at least one inner layer inside said surface layer of a material of greater strength than said surface layer.

11. A biomedical implant device as recited in claim 10, wherein said inner layer comprises sintered hydroxyapatite with a porosity significantly less than that of said surface layer.

12. A biomedical implant device as recited in claim 1, wherein said surface layer includes a plurality of surface projections having an average height of 5-1000 micrometers.

13. A biomedical implant device as recited in claim 5, wherein said surface layer includes a plurality of surface projections having heights of 5-1000 micrometers.

14. A biomedical implant device as recited in claim 1, wherein said surface layer includes a plurality of surface recesses having diameters of 0.5-500 micrometers.

15. A biomedical implant device as recited in claim 5, wherein said surface layer includes a plurality of surface recesses having diameters of 0.5-500 micrometers.

16. A biomedical implant device as recited in claim 1, wherein said medically operative part comprises a catheter and said support acts as a cuff surrounding said catheter.

17. A biomedical implant device as recited in claim 1, wherein said medically operative part comprises a drug reservoir and said support at least partially covers said drug reservoir.