Process for separating blood serum from blood

• US 4,803,153 A
• Filed: 03/18/1986
• Issued: 02/07/1989
• Est. Priority Date: 03/19/1985
• Status: Expired due to Fees

• Current Assignee: Nippon Paint Company Limited (Rainbow Light Limited)
• Original Assignee: Nippon Paint Company Limited (Rainbow Light Limited)
• Inventors: Ina, Kazuo, Ina, Hiroji, Shibata, Toshiko
• Primary Examiner(s): Brown, Johnnie R.
• Assistant Examiner(s): Stone, Jacqueline M.
• Application Number:
  US06/841,096
• Time in Patent Office: 1,057 Days
• Field of Search: 435/2, 514/465, 514/464, 514/834, 210/730, 424/195.1
• US Class Current: 435/2
• CPC Class Codes: A61P 7/04 Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
• CPC Class Codes: G01N 33/5002 Partitioning blood components

Abstract

A coagulant or hemostatic comprises, as an effective ingredient, at least one compound consisting of a lignan skelton having oxygen-containing side chains or rings.

Claims

1. A process for the separation of blood serum from blood, which comprises (a) placing at least one compound selected from the group consisting of d-sesamin, l-sesamin, paulownin, d-asarinin, l-asarinin, 2α

-paulownin, 6α

-paulownin, pinoresinol, d-eudesmin, l-pinoresinol β

-D-glucoside, l-pinoresinol, l-pinoresinol monomethyl ether β

-D-glucoside, epimagnolin, lirioresinol-B, syringaresinol (dl), lirioresinonB-dimethyl ether, phillyrin, magnolin, lirioresinol-A, 2α

, 6α

-d-sesamin, d-diaeudesmin, lirioresinol-C dimethyl ether (ddiayangambin) and sesamolin in a test tube which is used for separation of blood serum, and (b) placing blood into said test gube.

2. A process of claim 1, wherein the at least one compound is used in an amount ranging from 0.01 to 50 mg per 1 ml of the blood.