Apparatus and method for admixture blood warming
First Claim
Patent Images
1. A method for warming chilled erythrocytes to prevent hypothermia upon transfusion and to prevent hemolysis during warming, said method comprising the steps of:
- (a) admixing a quantity of the erythrocytes with a quantity of saline solution having a temperature in excess of 45°
C.; and
(b) conveying the admixture to a point of use.
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Abstract
Rapid mechanical admixing of blood products at a storage temperature of 4° C. with a saline solution in a temperature range of 50°-70° C. results in a mixture temperature sufficient to prevent hypothermia upon transfusion, which temperature rise per volume of the blood products is at a rate commensurate with the flow rate of transfusion equipment while not exceeding the temperature tolerance of the erythrocytes.
103 Citations
38 Claims
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1. A method for warming chilled erythrocytes to prevent hypothermia upon transfusion and to prevent hemolysis during warming, said method comprising the steps of:
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(a) admixing a quantity of the erythrocytes with a quantity of saline solution having a temperature in excess of 45°
C.; and(b) conveying the admixture to a point of use. - View Dependent Claims (2, 3, 4, 5)
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6. A method for warming stored blood products having a temperature in the range of 4°
- -10°
C. to a temperature in the range of 32°
C. to 39°
C. without significant hemolysis, said method comprising the steps of;(a) admixing a quantity of the blood products with a quantity of saline solution having a temperature in the range of more than 45°
C. to less than 80°
C.; and(b) conveying the admixture to a point of use. - View Dependent Claims (7, 8, 9, 10, 11, 12)
- -10°
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14. Apparatus for warming chilled blood products, said apparatus comprising in combination;
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(a) means for containing a quantity of the chilled blood products; (b) a saline solution heated to a temperature in the range of more than 45°
C. to less than 80°
C.;(c) means for housing said saline solution; and (d) means for admixing the blood products and said saline solution to provide an admixture having a temperature in the range of 32°
C. to 39°
C. - View Dependent Claims (13, 15, 16, 17, 18, 19, 20, 21, 22)
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23. Apparatus for admixing chilled blood products with a heated saline solution, said apparatus comprising in combination:
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(a) a first container for chilled blood products at a temperature in the range of 4°
C. to 10°
C.;(b) a second container for heated saline solution at a temperature in the range of more than 45°
C. to less than 80°
C.;(c) means for admixing the blood products and the saline solution to provide an admixture having a temperature in the range of 32°
C. to 39°
C.; and(d) means for conveying the admixture to a point of use. - View Dependent Claims (24, 25, 26, 27, 28, 29, 30)
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31. Apparatus for rapidly warming chilled and stored erythrocytes from a temperature in the range of 4°
- C. to 10°
C. to a temperature in the range of 32°
C. to 39°
C. without hemolysis, said apparatus comprising in combination;(a) a first container for containing a quantity of the erythrocytes; (b) a quantity of heated saline solution at a temperature in the range of 50°
C. to less than 80°
C.;(c) a second container for said saline solution; (d) mean for admixing the erythrocytes and said saline solution to effect a heat transfer from said saline solution to the erythrocytes; and (e) means for conveying the admixture to a point of use. - View Dependent Claims (32, 33, 34, 35, 36, 37, 38)
- C. to 10°
Specification