Hydrophilic polyurethane composition

• US 4,810,582 A
• Filed: 03/18/1988
• Issued: 03/07/1989
• Est. Priority Date: 11/12/1985
• Status: Expired due to Fees

• Current Assignee: Tyndale Plains-Hunter, Ltd.
• Original Assignee: Tyndale Plains-Hunter, Ltd.
• Inventors: Morgan, Ellen K., Gould, Francis E., Reduker, Stephen D.
• Primary Examiner(s): Buffalow, Edith
• Application Number:
  US07/169,936
• Time in Patent Office: 354 Days
• Field of Search: 427/2, 424/447, 424/445, 424/449, 424/432, 424/423, 424/443, 350/410, 128/114, 128/132 D, 128/348.1
• US Class Current: 428/423.1
• CPC Class Codes: A61L 27/26 Mixtures of macromolecular compounds
• CPC Class Codes: C08G 18/6674 with compounds of group C08G18/3203
• CPC Class Codes: C08L 75/04 Polyurethanes
• CPC Class Codes: C08L 75/08 from polyethers
• CPC Class Codes: G02B 1/043 Contact lenses
• CPC Class Codes: Y10T 428/31551 Of polyamidoester [polyurethane, polyisocyanate, polycarbamate, etc.]

Abstract

Water absorptive polyurethane composition, having high mechanical strength, is formed of A. about 25% to about 75% of a hydrophilic polyether polyurethane which is the reaction product of diethylene glycol and a polyoxyethylene glycol having a molecular weight of about 1000 to about 8000 with a polyisocyanate and B. about 75% to about 25% of a hydrophobic polyester polyurethane which is the reaction product of a polyfunctional polyester derived from the condensation of a polyol with a polybasic acid with a polyisocyanate.

Claims

1. As an article of manufacture, a shaped, three-dimensional structure formed of a water absorptive polyurethane composition comprising by weight a physical blend of A. about 25% to about 75% of a hydrophilic polyether polyurethane which is the reaction product of diethylene glycol and a polyoxyethylene glycol having a molecular weight of about 2000 to about 800 with a polyisocyanate and B. about 75% to about 25% of a hydrophobic polyester polyurethane which is the reaction product of a polyfunctional polyester derived from the condensation of a polyol with a polybasic acid with a polyisocyanate.

2. The article of manufacture in claim 1 wherein the structure is a film.

3. The article of manufacture in claim 1 wherein the structure is a burn dressing in the form of a film.

4. The article of manufacture in claim 1 wherein the structure contains a medicament.

5. The article of manufacture in claim 4 wherein the medicament is a hormone.

6. The article of manufacture in claim 4 wherein the medicament is a steroid.

7. The article of manufacture in claim 1 wherein the structure is in the form of an intrauterine device.

8. The article of manufacture in claim 7 wherein the intrauterine device contains a contraceptive composition.

9. The article of manufacture as defined in claim 1 wherein the structure is in the form of a diaphragm.

10. The article of manufacture as defined in claim 1 wherein the structure is in the form of a cannula.

11. The article of manufacture as defined in claim 10 wherein the cannula has distributed throughout its mass a medicament.

12. The article of manufacture as defined in claim 1 wherein the structure is in the form of an oral delivery system containing a pharmacologically active agent.

13. The article of manufacture as defined in claim 1 wherein the structure is in the form of a moisture-vapor permeable membrane.

14. The article of manufacture as defined in claim 1 wherein the structure has been molded.

15. The article of manufacture as defined in claim 1 wherein the structure is a contact lens.

16. The article of manufacture as defined in claim 1 wherein the structure is a corneal prosthesis.

17. The article of manufacture as defined in claim 1 wherein the structure is a surgical drape in the form of a film.

18. The article of manufacture as defined in claim 1 wherein the structure is in the form of a dialysis membrane.