Implantable medication infusion device and bolus generator therefor
First Claim
1. An implantable medication infusion device comprising:
- a housing comprising a main body, an interior cavity contiguous with said main body, and a fixed perforated barrier extending across said cavity in spaced relation to said main body;
a flexible bladder disposed in said cavity between said barrier and said main body, said bladder being attached along its periphery to said housing forming with said main body a sealed medication reservoir and with a remaining portion of said cavity a pressure sealed chamber;
pressurized inert gas in said chamber acting on said bladder forcing said bladder against said main body;
a recess in an exterior surface of said main body;
a passageway in said main body communicating between said recess and said reservoir;
a penetrable self-sealing septum positioned in said housing adjacent said recess and closing off said passageway whereby said reservoir can be filled by injection through said septum, filling of said reservoir moving said bladder toward said barrier, thereby compressing said inert gas and increasing the pressure thereof, and abutment of said bladder against said barrier providing a positive limit to reservoir capacity; and
flow restrictor means positioned in a recess in said main body, said flow restrictor means having an inlet connected to said reservoir, an outlet communicating with the exterior of said housing, and a flow restrictive passageway between said inlet and said outlet to limit flow of medication from said reservoir in response to pressure on said bladder to a predetermined rate.
1 Assignment
0 Petitions
Accused Products
Abstract
A flexible rubber bladder is disposed between a concave surface of a molded plastic base and a mirror image surface of a perforated molded plastic barrier, all enveloped by a molded plastic cover sealed to the base and defining a large volume cavity filled with inert gas under pressure. Injection of medication through a septum in the base fills a reservoir defined by the bladder and concave base surface and compresses the gas as the bladder moves to and against the barrier surface whereby the pressure exerted on the bladder forces medication through a metering outlet in the base and through an attached catheter to the infusion site. The free end of the catheter may be connected to a plastic protective cage for accumulating medication as droplets to dispense medication in bolus quantities.
147 Citations
30 Claims
-
1. An implantable medication infusion device comprising:
-
a housing comprising a main body, an interior cavity contiguous with said main body, and a fixed perforated barrier extending across said cavity in spaced relation to said main body; a flexible bladder disposed in said cavity between said barrier and said main body, said bladder being attached along its periphery to said housing forming with said main body a sealed medication reservoir and with a remaining portion of said cavity a pressure sealed chamber; pressurized inert gas in said chamber acting on said bladder forcing said bladder against said main body; a recess in an exterior surface of said main body; a passageway in said main body communicating between said recess and said reservoir; a penetrable self-sealing septum positioned in said housing adjacent said recess and closing off said passageway whereby said reservoir can be filled by injection through said septum, filling of said reservoir moving said bladder toward said barrier, thereby compressing said inert gas and increasing the pressure thereof, and abutment of said bladder against said barrier providing a positive limit to reservoir capacity; and flow restrictor means positioned in a recess in said main body, said flow restrictor means having an inlet connected to said reservoir, an outlet communicating with the exterior of said housing, and a flow restrictive passageway between said inlet and said outlet to limit flow of medication from said reservoir in response to pressure on said bladder to a predetermined rate. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
-
Specification