Biphasic waveforms for defibrillation

• US 4,821,723 A
• Filed: 02/27/1987
• Issued: 04/18/1989
• Est. Priority Date: 02/27/1987
• Status: Expired due to Term

• Current Assignee: Intermedics Incorporated
• Original Assignee: Intermedics Incorporated
• Inventors: Whistler, Stephen J., Ideker, Raymond E., Baker, Ross G. Jr., Calfee, Richard V., Haluska, Edward A.
• Primary Examiner(s): Jaworski, Francis
• Assistant Examiner(s): MANUEL, GEORGE C
• Application Number:
  US07/019,705
• Time in Patent Office: 781 Days
• Field of Search: 128/419 PG, 128/419 D
• US Class Current: 607/7
• CPC Class Codes: A61N 1/3906 characterised by the form of the shockwave
• CPC Class Codes: A61N 1/3956 Implantable devices for applying electric shocks to the heart, e.g. for cardioversion

Abstract

In a method and apparatus for defibrillating a heart in fibrillation, the onset of fibrillation of the heart is detected, and a biphasic waveform having only a first phase and a second phase is applied to the fibrillating heart. Each phase of the waveform is characterized by a predetermined time duration and by a predetermined polarity and magnitude of voltage, the duration of the first phase being greater than the duration of the second phase, and the initial voltage magnitude of the first phase being greater than that of the second phase. The biphasic waveform is applied by delivering it to a pair of patch electrodes affixed over and contoured to conform substantially to the surface of the right and left ventricles, respectively. The patch electrodes are affixed to either the epicardium or the pericardium. The left ventricular patch electrode is used as the cathode for the first phase of the applied biphasic waveform, and as the anode for the second phase. No further shocks are delivered to the heart pending detection of cardiac activity is response to the shocks delivered by the application of the biphasic waveform.

Claims

1. A method of defibrillating a heart in fibrillation, comprising the steps of:

detecting the onset of fibrillation of the heart, and

applying to the fibrillating heart a biphasic waveform having only a first phase and a second phase, each phase of the waveform being characterized by a predetermined time duration and by a predetermined polarity and magnitude of voltage, in which the duration of the first phase of the applied waveform is greater than the duration of the second phase.

2. The method of claim 1, in which:

the initial voltage magnitude of the first phase of the applied biphasic waveform is greater than the initial voltage magnitude of the second phase.

3. The method of claim 1, in which:

the step of applying is performed by delivering the biphasic waveform to a pair of patch electrodes affixed over and contoured to conform substantially to the surface of the right and left ventricles, respectively, of the heart.

4. The method of claim 3, in which:

the patch electrodes are affixed to the epicardium.

5. The method of claim 3, in which:

the patch electrodes are affixed to the pericardium.

6. The method of claim 3, in which:

the left ventricular patch electrode is used as the cathode for the first phase of the applied biphasic waveform, and as the anode for the second phase.

7. A method of terminating ventricular fibrillation by direct internal defibrillation, comprising the steps of:

detecting the onset of ventricular defibrillation,

responding to that detection by applying a first defibrillation shock directly to the ventricles, in which the shock is a voltage of predetermined magnitude, polarity and duration,

immediately thereafter applying a second defibrillation shock directly to the ventricles, in which the second shock is a voltage of opposite polarity and shorter duration than the initially applied shock, and

ceasing the delivery of any further defibrillation shocks after the second shock, pending detection of the activity of the heart in response to the first and second shocks.

8. The method of claim 7, in which:

the second shock is of lower magnitude than the initially applied shock.

10. The method of claim 8, in which

the first phase is a voltage of greater magnitude than the second phase.

11. The method of claim 10, further including

making the gap between the confronting borders of the two patch electrodes of sufficient width to prevent shunting of current between the confronting borders during application of the defibrillating waveform.

12. The method of claim 11, further including

making the gap between the confronting borders of the patch electrodes of sufficient width to accommodate the ventricular septum therein, to establish preferential current flow through one ventricle across the septum to the free wall of the other ventricle during application of a defibrillating waveform to the electrodes.

13. The method of claim 12, further including

making the gap between the confronting borders of the patch electrodes of sufficient width to accommodate the left anterior descending coronary artery and the posterior descending coronary artery therein, to avoid vascular damage from the application of defibrillating waveforms to the electrodes.

16. The implantable defibrillator of claim 8 wherein

said delivering means comprises a pair of patch electrodes, one having a size and shape to be placed over the right ventricle and the other having a size and shape to be placed over the left ventricle, the pair of electrodes cooperating to encompass virtually the entire ventricular myocardium therebetween.

9. A method of defibrillating the heart, comprising the steps of:

placing a first patch electrode over the right ventricle of the heart, configured to conform substantially to the shape and size of the surface of the right ventricle,

placing a second path electrode over the left ventricle of the heart, configured to conform substantially to the shape and size of the surface of the left ventricle in spaced relationship to the first patch electrode to form a uniform gap between confronting borders of the two patch electrodes in the region of the ventricular septum, while encompassing a substantial portion of the ventricular myocardium between the two patch electrode, toward establishing a uniform potential gradient field through out the entire ventricular mass when a defibrillating electrical waveform is applied to the electrodes, and

applying a defibrillating electrical waveform constituting a biphasic shock having a first phase of longer duration than the second phase thereof, to the electrodes.

14. An implantable defibrillator, comprising

means for detecting fibrillation,

electrical generating means responsive to the detection of fibrillation for producing a biphasic waveform in which each phase is characterized by an electrical impulse of predetermined polarity, magnitude and duration, the first phase being of greater duration and magnitude than and of opposite polarity to the second phase, and

means for delivering said waveform to provide electrical shock to the ventricles of the heart.

15. The implantable defibrillator of claim 14, wherein

said generating means produces biphasic waveforms in which each phase is a truncated exponential pulse.