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Pyroelectric enzyme detector

  • US 4,829,003 A
  • Filed: 08/28/1986
  • Issued: 05/09/1989
  • Est. Priority Date: 08/28/1986
  • Status: Expired due to Fees
First Claim
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1. A pyroelectric sensor for detecting an enzyme or enzymatic substrate in a gas or liquid stream comprising:

  • (a) a pyroelectirc laminate having an upper and lower surface comprised of a pyroelectric material sandwiched between upper and lower conducting means to act as electrodes for conducting an electrical response from said pyroelectric material;

    (b) electronic circuit means connected to said electrodes to measure thermally induced electric current from said pyroelectric material;

    (c) a reactant selected from the group consisting of an enzyme and an enzymatic substrate reactable respectively with a corresponding enzyme or substrate to produce a thermally detectable endothermic or exothermic reaction, said reactant being chemically immobilized on a surface on one of said conducting means;

    (d) a support means supporting said laminate;

    (e) a plate means resting on the upper surface of said supported laminate, said plate means having a longitudinal flow channel for said gas or liquid stream disposed above and communicating with the upper surface of said laminated and said plate and means having a recess communicating with said upper surface for accomodating said electronic circuit means;

    (f) an inlet means passing through said plate means communicating with said flow channel near one end thereof; and

    (g) an outlet means passing through said plate means communicating with said flow channel near an end opposite said inlet means.

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