Method and system for treatment of sleep apnea

• US 4,830,008 A
• Filed: 02/16/1988
• Issued: 05/16/1989
• Est. Priority Date: 04/24/1987
• Status: Expired due to Term

• Current Assignee: Jeffrey A MEER Revocable Living Trust
• Original Assignee: Jeffrey A. Meer
• Inventors: Meer, Jeffrey A.
• Primary Examiner(s): Jaworski, Francis
• Assistant Examiner(s): MANUEL, GEORGE C
• Application Number:
  US07/156,186
• Time in Patent Office: 455 Days
• Field of Search: 128/419.6, 128/421, 128/716, 128/720, 128/721, 128/204.23, 128/905
• US Class Current: 607/42
• CPC Class Codes: A61N 1/3601 of respiratory organs

Abstract

A method for treatment of sleep-apnea syndrome in a patient is disclosed as including mointoring inspiratory effort and generating electrical signals in response to the step of monitoring in order to stimulate those nerves which activate the patient'"'"'s upper airway muscles to contract in order to maintain upper airway patency. A system (10) for such treatment is disclosed as including a monitor (14) capable of monitoring inspiratory effort, and an elecrtrical signal generating mechanism (16) coupled to the monitor (14) for generating electrical signals, to affect the patient'"'"'s upper airway muscles in order to thereby maintain upper airway patency.

Claims

1. A method for treatment of sleep-apnea syndrome in a patient, the method comprising the steps of:

monitoring inspiratory effort;

generating electrical signals in response to the step of monitoring; and

applying said electrical signals to those nerves which activate the patient'"'"'s upper airway muscles to contract in order to maintain upper airway patency.

2. A method as in claim 1 further including the step of sensing upper airway muscle activity and inhibiting the release of electrical signals if normal upper airway activity is detected.

3. A method as in claim 1 or 2 further including the step of activating those muscles included in the group consisting of the diaphragm or sternomastoid muscles as necessary to cause inspiration at a predetermined rate when no inspiratory effort is sensed by said monitor.

4. A method as in claim 1 wherein the upper airway muscles include one or more of the muscles in the group consisting of geniohyoid, genioglossus, digastric, stylopharyngei or mylohyoid.

5. A method as in claim 4 wherein effecting the upper airway muscles includes moving the patient'"'"'s tongue anteriorly.

6. A method as in claim 1 wherein monitoring inspiratory effort includes monitoring contraction of the patient'"'"'s inspiratory muscles.

7. A method as in claim 6 wherein monitoring the inspiratory effort includes comparing the contraction of the patient'"'"'s inspiratory muscles to a predetermined threshold contraction.

8. A method as in claim 7 wherein the electrical signals are generated at the appropriate instant during the respiratory cycle.

9. A method as in claim 1 wherein monitoring inspiratory effort includes monitoring intrathoracic pressure.

10. A method as in claim 9 wherein monitoring the inspiratory effort sensed includes comparing the intrathoracic pressure to a predetermined threshold of intrathoracic pressure.

11. A method as in claim 9 wherein the electrical signals are generated at the appropriate instant during the respiratory cycle.

12. A system (10) for treatment of sleep-apnea syndrome in a patient comprising:

monitoring means (14) capable of monitoring inspiratory effort; and

electrical signal generating means (16) coupled to said monitor (14) for generating electrical signals to effect those nerves which activate the patient'"'"'s upper airway muscles to contract as necessary to thereby maintain upper airway patency.

13. A system as in claim 12 wherein said monitor (14) senses action potentials in those nerves which innervate those muscles which maintain upper airway patency.

14. A system (10) as in claim 12 or 13 further including a sensor lead (18) having first and second ends (20, 22);

said first end (20) being communicated to said monitor (14) and said second end (22) including a sensor electrode (24) attached to the inspiratory muscles for receiving inspiratory information from the inspiratory muscles and for conveying the information received by said sensor electrode (24) along lead (18) to said monitor (14).

15. A system (10) as in claim 14 further including an effector lead (26) having first and second ends (28, 30);

said first end (28) being connected to said electrical signal generating means (16) and said second end (30) including an effector electrode (32) for transmitting electrical signals sent via effector lead (26) to those nerves which activate the upper airway muscles.

16. A system as in claim 15 wherein said effector lead (26) is also communicated to said monitor via said electrical signal generating means 16 (14) to sense action potentials at the effector electrode (32) in those nerves which innervate those inspiratory muscles which maintain upper airway patency.

17. A system (10) as in claim 16 wherein said effector electrode (32) initiates excitation in one or more of the muscles in the group consisting of geniohyoid, genioglossus, digastric, stylopharyngei or mylohyoid.

18. A system (10) as in claim 17 wherein said effector electrode (32) initiates excitation in the genioglossus muscle and thereby moves the patient'"'"'s tongue anteriorly.

19. A system (10) as in claim 14 wherein said monitor (14) monitors contraction and expansion of the patient'"'"'s inspiratory muscles.

20. A system (10) as in claim 14 wherein said monitor (14) monitors intrathoracic pressure.

21. A system (10) as in claim 14 wherein said electrical signal generating means (16) is programmable with respect to providing electrical stimuli output in response to predetermined input messages.

22. A system (10) as in claim 21 wherein said programmable electrical signal generating means (16) is programmable with respect to voltage, current, pulse width and frequency of electrical stimuli provided.

23. A method of the type used to treat sleep-apnea syndrome including monitoring inspiratory effort characterized by generating electrical signals in response to the monitoring to stimulate those nerves which activate the patient'"'"'s upper airway muscles to contract thereby to maintain upper airway patency and sensing upper airway muscle activity and inhibiting the release of electrical signals if normal upper airway activity is detected.