Injectable infusion pump apparatus for implanting long-term dispensing module and medication in an animal and method therefor

• US 4,834,704 A
• Filed: 04/13/1988
• Issued: 05/30/1989
• Est. Priority Date: 04/13/1988
• Status: Expired due to Fees

• Current Assignee: Eaton Corp. (Wisconsin) (Eaton Corporation PLC.)
• Original Assignee: Eaton Corp. (Wisconsin) (Eaton Corporation PLC.)
• Inventors: Reinicke, Robert H.
• Primary Examiner(s): Pellegrino, Stephen C.
• Application Number:
  US07/181,134
• Time in Patent Office: 412 Days
• Field of Search: 604/57, 604/59, 604/60, 604/93, 604/96, 604/103, 604/132, 604/891.1, 604/51, 128/DIG. 2
• US Class Current: 604/506
• CPC Class Codes: A61M 37/0069 Devices for implanting pellets, e.g. markers or solid medicaments for introducing of radioactive sources for interstitial radiation therapy, i.e. brachytherapy A61N5/1027
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/152 pressurised by contraction of elastic reservoirs containers for dispensing contents by contraction of an elastic bag provided therein, in general B65D83/0061

Abstract

A two-stage injection device has a resiliently expandable medication reservoir stored in collapsed state within the cannula. After inserting the cannula through the skin into an animal cavity, depression of a first stage element injects the reservoir out the cannula into the cavity. Depression of a second stage element fills the reservoir with fluid medication, elastically expanding the reservoir. The injection apparatus is withdrawn, leaving the reservoir implanted in the cavity, continuously infusing medication for a period up to hundreds of days through a restrictor orifice under the pressure of the elastically stretched walls of the reservoir.

Claims

1. Injectable infusion pump apparatus for implanting a long-term dispensing module and medication into a body cavity of an animal comprising:

an elongate body having a cannula extending from one end and a chamber communicating with said cannula open to an opposite end, the distal end of said cannula being cut at an acute angle;

a plug slidably retained within said cannula, said plug having a fluid flow restrictor orifice therethrough;

a hollow elastic reservoir having said plug affixed in one end to seal off said one end and having a self-sealing septum at an opposite end, said reservoir being disposed within said cannula;

a syringe barrel slidably disposed in said chamber having a tubular extension projecting into said cannula abutting said opposite end of said reservoir, the distal end of said extension having a reduced-size projection penetrating said septum, said syringe barrel having a fluid receiving cavity and a fluid flow passage leading therefrom through said tubular extension and said reduced-size projection into said reservoir;

a quantity of fluid medication in said syringe barrel cavity; and

a plunger slidably disposed in said syringe barrel cavity;

depression of said syringe barrel into said body chamber causing said extension to eject said reservoir and said plug out the distal end of said cannula; and

depression of said plunger into said syringe barrel cavity injecting said medication into said reservoir through said fluid flow passage to elastically expand said reservoir, elasticity of said expanded reservoir providing a pressure on medication therein to force said medication through said flow restrictor orifice at a predetermined rate.

2. The injectable infusion pump apparatus as defined in claim 1 wherein said plug has an elongated stem portion extending within said reservoir toward said opposite end of said reservoir, said stem terminating in spaced relation to an internal end of said reduced-size projection.

3. The injectable infusion pump apparatus as defined in claim 2 wherein said flow restrictor orifice comprises an elongated capillary passageway extending through said plug.

4. The injectable infusion pump apparatus as defined in claim 2 wherein said stem has a plurality of grooves in an external surface of said stem.

5. The injectable infusion pump apparatus as defined in claim 4 wherein said reservoir is in intimate contact with said stem along its length and said grooves form fluid flow passageways toward said one end of said reservoir.

6. The injectable influsion pump apparatus as defined in claim 1 wherein an external end of said plug is formed at an acute angle to be substantially flush with said distal end of said cannula.

7. The injectable infusion pump apparatus as defined in claim 1 further comprising clamping means disposed around said opposite end of said reservoir exerting a closing force on said septum.

8. The injectable infusion pump apparatus as defined in claim 1 wherein said reduced-size projection comprises a tube affixed in the distal end of said extension.

9. The injectable infusion pump apparatus as defined in claim 1 further comprising locking means on said body and said syringe barrel cooperably engagable when said syringe barrel is depressed a predetermined amount to lock said syringe barrel depressed.

10. The injectable infusion pump apparatus as defined in claim 9 wherein said locking means automatically engages by depressing said syringe barrel said predetermined amount.

11. The injectable infusion pump apparatus as defined in claim 10 wherein said locking means comprises resilient hooks on said syringe barrel deflected into locking engagement with catch means on said body upon depression of said syringe barrel said predetermined amount.

12. The injectable infusion pump apparatus as defined in claim 1 wherein said body and said syringe barrel are provided with finger grip means to faciliate depression of said syringe barrel into said body.

13. A method of injecting a long-term dispensing module and medication into an animal comprising:

providing injectable infusion pump apparatus as defined in claim 1;

inserting said cannula into a body cavity of an animal by penetrating body tissue covering said body cavity;

depressing said syringe barrel into said chamber to eject said reservoir and said plug from said cannula through said distal end of said cannula;

depressing said plunger into said syringe barrel cavity to inject medication from said cavity through said fluid flow passageway into said reservoir, thereby elastically expanding said reservoir; and

withdrawing said cannula from said animal body cavity, thereby separating said tubular extension and said reservoir and removing said reduced-size projection from said septum;

said reservoir elastically contracting to force said medication through said flow restrictor orifice at a predetermined rate.