Bone cement

• US 4,837,279 A
• Filed: 02/22/1988
• Issued: 06/06/1989
• Est. Priority Date: 02/22/1988
• Status: Expired due to Term

• Current Assignee: Howmedica Osteonics Corp. (Stryker Corporation)
• Original Assignee: Pfizer Hospital Products Group, Inc. (Pfizer Inc.)
• Inventors: Arroyo, Nestor A.
• Primary Examiner(s): Jacobs, Lewis T.
• Assistant Examiner(s): BUTTNER, DAVID J
• Application Number:
  US07/158,472
• Time in Patent Office: 470 Days
• Field of Search: 523/116, 523/117, 523/118, 525/309, 525/937, 525/193
• US Class Current: 525/193
• CPC Class Codes: A61F 2002/4631 the prosthesis being specially adapted for being cemented
• CPC Class Codes: A61L 24/043 Mixtures of macromolecular materials
• CPC Class Codes: A61L 2430/02 for reconstruction of bones; weight-bearing implants
• CPC Class Codes: C08L 33/12 Homopolymers or copolymers of methyl methacrylate
• CPC Class Codes: Y10S 525/937 Utility as body contact e.g. implant, contact lens or I.U.D.

Abstract

There is disclosed a bone cement composition comprising (a) a liquid component comprising a monomer of an acrylic ester and (b) a powdered component comprising, based on the weight of the powdered component,

(i) from 0 to about 20 percent of a methyl methacrylate homopolymer,

(ii) from about 30 to about 60 percent of a methyl methacrylate-styrene copolymer, and

(iii) from about 30 to about 60 percent of a methyl methacrylate-butyl methacrylate copolymer.

Claims

1. A bone cement composition comprising:

(a) a liquid component comprising a monomer of an acrylic ester, and

(b) a powdered component comprising, based on the weight of the powdered component,

(i) from 0 to about 20 percent of a methyl methacrylate homopolymer,

(ii) from about 30 to about 60 percent of a methyl methacrylate-styrene copolymer,

(iii) from about 30 to about 60 percent of a methyl methacrylate-butyl methacrylate copolymer.

2. The composition of claim 1 further comprising a free radical stabilizer and a polymerization accelerator incorporated in component (a).

3. The composition of claim 2 wherein said free radical stabilizer is hydroquinone and said polymerization accelerator is N,N-dimethyl paratoluidine.

4. The composition of claim 1 wherein component b(i) is present at about 1 to about 20 percent, based on the weight of the powdered component.

5. The composition of claim 1 essentially free of component (b)(i).

6. The composition of claim 5 wherein component (b)(ii) is present at about 50 percent by weight and component (b)(iii) is present at about 50 percent by weight.

7. The composition of claim 1 further comprising an opacifying agent in the powdered component.

8. A process for the production of a bone cement composition comprising combining:

(a) a liquid component comprising a monomer of an acrylic ester with

(b) a powdered component comprising, based on the weight of the powdered component,

(i) from 0 to about 20 percent of a methyl methacrylate homopolymer,

(ii) from about 30 to about 60 percent of a methyl methacrylate-styrene copolymer,

(iii) from about 30 to about 60 percent of a methyl methacrylate-butyl methacrylate copolymer.