Method and apparatus for adaptive closed loop electrical stimulation of muscles

• US 4,838,272 A
• Filed: 08/19/1987
• Issued: 06/13/1989
• Est. Priority Date: 08/19/1987
• Status: Expired due to Term

• Current Assignee: Regents of the University of California (University of California)
• Original Assignee: Regents of the University of California (University of California)
• Inventors: Lieber, Richard L.
• Primary Examiner(s): Jaworski, Francis
• Assistant Examiner(s): Manuel, George
• Application Number:
  US07/087,470
• Time in Patent Office: 664 Days
• Field of Search: 128/421, 128/422, 128/423 W, 128/25 B, 128/25 R
• US Class Current: 607/48
• CPC Class Codes: A61N 1/36003 of motor muscles, e.g. for walking assistance

Abstract

A method and apparatus for strengthening skeletal muscles through maximizing muscle tension in which electrical stimulation signals are applied to the selected muscles at a predetermined frequency, pulse width, and amplitude, and work output by the muscles in response to stimulation signals is determined over a fixed period of time. The work output is compared to a defined value which can be a target value or a value measured during a previous stimulation period. The amount of electrical energy coupled into the muscles by the stimulation signals is varied in response to the results of the comparison in order to maximize the amount of work output by the muscles during a treatment period. This is accomplished by adjusting the frequency or pulse width during stimulation treatment in response to the work output measured.

Claims

1. A method of strengthening skeletal muscles, comprising the steps of:

applying to said muscles a series of stimulation signals having predetermined signal characteristics comprising frequency, pulse-width, and amplitude so as to couple electrical energy into said muscles;

measuring work output by the muscles in response to a stimulation signal over a predetermined period N;

comparing the measured work output to a prestored work value and providing a difference therebetween; and

adjusting the energy coupled into said muscles by adjusting signal characteristics of subsequently applied stimulation signals in response to said difference.

8. The method of claim 1 wherein said step of applying stimulation signals to said muscles further comprises generating stimulation signals at a frequency in the range of about 10 to 100 Hertz.

9. The method of claim 1 wherein said step of measuring the work output comprises the steps of:

measuring torque generated by said muscles during stimulation; and

integrating said torque over a predetermined time interval to produce a measured work value.

10. The method of claim 9 further comprising the step of storing a precomputed work value as said prestored work value.

11. The method of claim 9 further comprising the steps of:

measuring torque generated by said muscles during stimulation during a predefined period N-1;

integrating said torque over said period N-1;

storing results of said integrating step as said prestored work value; and

comparing said measured work output for the period N to said prestored work value for the period N-1.

12. The method of claim 1 wherein said step of measuring the work output comprises the steps of:

measuring electromyogram (EMG) output generated by said muscles during stimulation; and

integrating said EMG over a predetermined time interval to produce a measured work value.

13. The method of claim 12 further comprising the step of storing a precomputed work value as said prestored work value.

14. The method of claim 12 further comprising the steps of:

measuring EMG generated by said muscles during stimulation during a predefined period N-1;

integrating said EMG over said period N-1;

storing results of said integrating step as said prestored work value; and

comparing said measured work output for the period N to said prestored work value for the period N-1.

15. The method of claim 1 further comprising the steps of:

storing measurements of work output in a data storage element;

storing frequency of stimulation corresponding to said measurements of work output in a second data storage element; and

transferring said stored work output and frequency data to a data display.

2. A method of strengthening skeletal muscles, comprising the steps of:

applying a series of stimulation signals to the muscles having predetermined signal characteristics comprising frequency, pulse-width, and amplitude;

measuring work output by said muscles in response to a stimulation signal;

comparing the measured work output to a prestored work value and providing a difference therebetween;

adjusting the frequency of subsequently applied stimulation signals in response to said difference; and

returning to said measuring step.

3. The method of claim 2 wherein said step of adjusting the frequency of said stimulation signals further comprises the steps of:

incrementing the frequency by a predetermined frequency step each time an increase in work output is measured as between adjacent periods up to a predetermined maximum frequency limit; and

decrementing said frequency by said predetermined frequency step each time a decrease in work output is measured between adjacent periods down to a predetermined minimum frequency limit.

4. The method of claim 3 wherein said predetermined frequency step is on the order of 4-6 Hertz.

5. The method of claim 3 wherein:

said stimulation signal has a frequency varying over about a 10-100 Hertz frequency range applied to said muscles for an initial stimulation period;

said torque is generated by said muscles during said initial period; and

said maximum frequency limit is set equal to a frequency within said range for which said torque has a maximum value.

6. The method of claim 3 further comprising the steps of:

applying a stimulation signal having a frequency varying over about a 10-100 Hertz frequency range to said muscles for an initial stimulation period;

measuring the EMG generated by said muscles during said initial period; and

setting said maximum frequency limit equal to a frequency within said range for which said EMG has a maximum value.

7. A method of strengthening skeletal muscles through maximizing muscle tension, comprising the steps of:

applying a series of stimulation signals to the muscles having predetermined signal characteristics comprising frequency, pulse-width, and amplitude;

measuring work output by said muscles in response to a stimulation signal;

comparing the measured work output to a prestored work value and providing a difference therebetween; and

adjusting the pulse width of subsequently applied stimulation signals in response to said difference.

16. An apparatus for exercising skeletal muscles through obtaining maximum tension, comprising:

at least one electrode adapted to be electrically coupled to said muscles;

at least one stimulation means connected to said electrode for coupling electrical energy into said muscles by generating electrical stimulation signals having predetermined characteristics comprising frequency, pulse-width, and amplitude to which the muscles are responsive;

work detection means adapted to be operatively coupled to said muscles for measuring work output by said muscles during stimulation;

comparison means connected to said work detection means for comparing said work measured with a prestored work value and for providing a difference therebetween; and

adjustment means connected to said comparison means and said stimulation means for adjusting the signal characteristics of said stimulation signals and incrementing and decrementing the electrical energy adapted to be coupled into the muscles by said stimulation signals in response to decreases and increases respectively in said difference.

17. The apparatus of claim 16 wherein said adjustment means further comprises frequency adjustment means for incrementing and decrementing the frequency of stimulation signals in response to decreases and increases respectively in said difference.

18. The apparatus of claim 17 wherein said frequency adjustment means comprises:

a torque transducer adapted to be coupled to body surfaces adjacent said muscles for generating an output signal proportional to a torque exerted during motion of said muscles;

synchronization means connected in series with said torque transducer for gating the output signal of said transducer at predetermined time intervals; and

integration means connected in series with said synchronization means for receiving transducer output signals over a predetermined time interval and integrating a magnitude thereof over that interval so as to produce an integrand representative of work exerted by said muscles; and

input means for transferring the integrand to said comparison means.

19. The apparatus of claim 17 wherein said frequency adjustment means comprises:

an EMG transducer adapted to be coupled to body surfaces adjacent said muscles for generating an output signal proportional to a torque exerted during motion of said muscles;

synchronization means connected in series with said torque transducer for gating the output signal of said transducer at predetermined time intervals; and

integration means connected in series with said synchronization means for receiving transducer output signals over a predetermined time interval and integrating a magnitude thereof over that interval so as to produce an integrand representative of work exerted by said muscles; and

input means for transferring the integrand to said comparison means.

20. The apparatus of claim 18 wherein said control means comprises a portable programmable microprocessor device which further comprises:

a central processing unit for controlling the transfer of data and stimulation signal characteristics in response to input commands and for computing a difference between prestored work values and measured work values;

data storage means connected to said work detection means and said central processing unit for storing measured work values;

program storage means connected to said central processing unit for storing commands used for setting signal characteristics in said central processing means, for computing said difference in work output, and for terminating exercise; and

input/output control means connected to said central processing unit for transferring stimulation characteristic data and measured work values into said microprocessor device and for transferring signal control parameters from said microprocessor device to said stimulation means stimulator.

21. The apparatus of claim 20 further comprising data transfer means connected to said data storage means for retrieving stored measured work data and stimulation frequency values stored in said microprocessor device and for transferring same to other apparatus for analysis and display.

22. The apparatus of claim 16 wherein said adjustment means further comprises pulse adjustment means for incrementing and decrementing a pulse width of said stimulation signals in response to measured decreases and increases respectively in the measured work.

23. The apparatus of claim 22 wherein said pulse adjustment means further comprises:

a torque transducer adapted to be coupled to body surfaces adjacent said muscles for generating an output signal proportional to a torque exerted during motion of said muscles;

synchronization means connected in series with said torque transducer for gating the output signal of said transducer at predetermined time intervals; and

integration means connected in series with said synchronization means for receiving transducer output signals over a predetermined time interval and integrating a magnitude thereof over that interval so as to produce an integrand representative of work exerted by said muscles; and

input means for transferring the integrand to said comparison means.

24. The apparatus of claim 22 wherein said pulse adjustment means further comprises:

an EMG transducer adapted to be coupled to body surfaces adjacent said muscles for generating an output signal proportional to a torque exerted during motion of said muscles;

synchronization means connected in series with said torque transducer for gating the output signal of said transducer at predetermined time intervals; and

integration means connected in series with said synchronization means for receiving transducer output signals over a predetermined time interval and integrating a magnitude thereof over that interval so as to produce an integrand representative of work exerted by said muscles; and

input means for transferring the integrand to said comparison means.