Portable controlled release osmotic infusion device
First Claim
1. A portable controlled release osmotic infusion device comprising:
- (a) a housing, containing;
(b) a fluid-imbibing unit, comprising a solvent-containing chamber and a solute-containing chamber;
the two chambers separated by a semipermeable membrane assembly, said assembly comprising a two-layer laminate of a semipermeable membrane layer and a solute-impermeable sealing layer;
(c) a drug-containing chamber separated from the fluid-imbibing unit by a leakproof impermeable elastic diaphragm; and
(d) an activating mechanism which breaks said sealing layer;
said activating mechanism being disposed adjacent to, and in contact with, said fluid-imbibing unit;
said portable controlled release osmotic infusion device being characterized in that it may be filled with the contents of said solvent-containing, solute-containing and drug-containing chambers, and stored in an inactive state until required.
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Accused Products
Abstract
A portable controlled release osmotic infusion device, which can be activated on demand by the user, comprising a rigid housing containing:
a. a fluid-imbibing assembly, comprising a solvent-containing chamber and a solute-containing chamber; the two chambers separated by a rigid semipermeable membrane covered by a thin taut foil seal,
b. a drug-containing chamber separated from the fluid-imbibing assembly by a leakproof impermeable elastic diaphragm, which expands into the drug-containing chamber in use and drives the drug through a dispersing orifice at a steady rate, and
c. an activating device which ruptures the foil seal described in (a) above and initiates the osmotic action of the device.
The osmotic device is filled with drug in solution or suspended form during manufacture and can be stored without deterioration of the contents for prolonged periods of time.
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Citations
11 Claims
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1. A portable controlled release osmotic infusion device comprising:
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(a) a housing, containing; (b) a fluid-imbibing unit, comprising a solvent-containing chamber and a solute-containing chamber;
the two chambers separated by a semipermeable membrane assembly, said assembly comprising a two-layer laminate of a semipermeable membrane layer and a solute-impermeable sealing layer;(c) a drug-containing chamber separated from the fluid-imbibing unit by a leakproof impermeable elastic diaphragm; and (d) an activating mechanism which breaks said sealing layer;
said activating mechanism being disposed adjacent to, and in contact with, said fluid-imbibing unit;said portable controlled release osmotic infusion device being characterized in that it may be filled with the contents of said solvent-containing, solute-containing and drug-containing chambers, and stored in an inactive state until required. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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Specification