3-aralkyl-2-mercaptoyridines as dopamine-.beta.-hydroxylase inhibitors
First Claim
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1. A compound of structure (I):
- ##STR12## in which;
X1 to X5 are hydrogen, halogen, hydroxy, or C1-4 alkoxy;
n is 1 to 5; and
R is hydrogen or C1-4 alkyl;
or a pharmaceutically acceptable salt thereof.
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Abstract
Disclosed are novel substituted 3-aralkyl-2-mercaptopyridines of the structure: ##STR1## processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them and their use in therapy in particular as dopamine-β-hydroxylase inhibitors.
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10 Claims
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1. A compound of structure (I):
- ##STR12## in which;
X1 to X5 are hydrogen, halogen, hydroxy, or C1-4 alkoxy;n is 1 to 5; and R is hydrogen or C1-4 alkyl;
or a pharmaceutically acceptable salt thereof. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
- ##STR12## in which;
Specification