Specimen distributing system

• US 4,841,786 A
• Filed: 06/06/1988
• Issued: 06/27/1989
• Est. Priority Date: 05/02/1986
• Status: Expired due to Fees

• Current Assignee: Fh-O Forschungs And Entwicklungs GMBH
• Original Assignee: Fh-O Forschungs And Entwicklungs GMBH
• Inventors: Schulz, Peter
• Primary Examiner(s): Levy, Stewart J.
• Assistant Examiner(s): Raevis, Robert R.
• Application Number:
  US07/202,393
• Time in Patent Office: 386 Days
• Field of Search: 73/864.01, 73/864.11, 73/864.12, 73/864.22, 73/864.24, 73/864.25, 73/864.31, 73/864.34, 73/864.35, 73/290 V, 422/64, 422/67, 422/100
• US Class Current: 73/864.25
• CPC Class Codes: G01N 2035/1025 Fluid level sensing
• CPC Class Codes: G01N 2035/1032 Dilution or aliquotting
• CPC Class Codes: G01N 2035/1076 plurality or independently movable heads
• CPC Class Codes: G01N 35/1004 Cleaning sample transfer devices
• CPC Class Codes: G01N 35/1072 with provision for selective pipetting of individual channels
• CPC Class Codes: G01N 35/1083 with one horizontal degree of freedom

Abstract

A specimen distributing system for the remote-controlled extraction of sample specimens is provided wherein manipulator units supporting pipettes are movable horizontally and vertically and specific quantities of sample fluids may be transferred from primary containers to secondary containers. The distributing system comprises a table unit which is rotatable around a central vertical axis, with secondary containers forming container assemblies arranged around the circumference of the table unit and positioned peripheral to the table unit. The distributing system furthermore comprises a washing device for the pipettes and a central control unit. Manipulator units are supported by the table unit, and distributed around the central axis, and primary containers forming a container assembly are positioned peripheral to the table unit. The washing station is arranged between the last secondary container and the primary container assembly.

Claims

1. A specimen distribution apparatus for automated extraction of specified quantities of sample specimens from primary containers and transfer of said sample specimens to secondary containers for testing, said apparatus comprising:

a circular table rotatable about a central vertical axis;

a plurality of manipulator units supported on said table and spaced a radial distance from said central vertical axis, each said manipulator unit movable back and forth in a linear direction perpendicular to the radius of said table and each said manipulator unit supporting at least one pipette movable in vertical direction;

a plurality of said primary containers forming a primary container assembly, said primary container assembly radially arranged with respect to said central vertical axis, extending beyond the circumference of and radially movable with respect to said central vertical axis of said table;

a plurality of said secondary containers forming secondary container assemblies, each said secondary container assembly arranged radially with respect to said central vertical axis, extending beyond said circumference of and radially movable with respect to said central vertical axis of said table and circumferentially aligned with said primary container assembly; and

a washing device for cleaning said pipettes circumferentially aligned with said primary and said secondary container assemblies and between the last said secondary container assembly and said primary container assembly with respect to said rotatable direction of said table.

2. A specimen distributing apparatus in accordance with claim 1, characterized in that each said manipulator unit is spaced the same said radial distance from said central vertical axis.

3. A specimen distributing apparatus in accordance with claim 1, additionally comprising at least one dilutor means arranged on said table radially with respect to said central vertical axis.

4. A specimen distributing apparatus in accordance with claim 1, characterized in that a lead connects each said pipette to said at least one dilutor means, and a pressure sensor is provided in communication with said lead and said dilutor means.

5. A specimen distribution apparatus in accordance with claim 1, additionally comprising a vibration imparting device and a vibration sensing device in communication with each said pipette, and a comparator means which compares the nominal frequency to the measured frequency of the end of each said pipette.

6. A specimen distribution apparatus for automated extraction of specified quantities of sample specimens from primary containers and transfer of said sample specimens to secondary containers for testing, said apparatus comprising:

a circular table rotatable about a central vertical axis;

a plurality of manipulator units supported on said table and spaced the same radial distance from said central vertical axis, each said manipulator unit movable back and forth in a linear direction perpendicular to the radius of said table and each said manipulator unit supporting at least one pipette movable in vertical direction;

a plurality of said primary containers forming a primary container assembly, said primary container assembly radially arranged with respect to said central vertical axis, extending beyond the circumference of and radially movable with respect to said central vertical axis of said table;

a plurality of said secondary containers forming secondary container assemblies, each said secondary container assembly arranged radially with respect to said central vertical axis, extending beyond said circumference of and radially movable with respect to said central vertical axis of said table and circumferentially aligned with said primary container assembly; and

a washing device for cleaning said pipettes circumferentially aligned with said primary and said secondary container assemblies and between the last said secondary container assembly and said primary container assembly with respect to said rotatable direction of said table, each said manipulator unit comprises a vertically oriented support with a horizontally oriented cross-piece extending beyond said circumference of said table over one of said container assemblies, said vertically oriented support is movable back and forth on a guide unit aligned perpendicular to the radius of said table, and said horizontally oriented cross-piece supports said at least one pipette and is vertically adjustable on said vertically oriented support.

7. A specimen distributing apparatus in accordance with claim 6, additionally comprising at least one dilutor means arranged on said table radially with respect to said central vertical axis.

8. A specimen distributing apparatus in accordance with claim 7, characterized in that a lead connects each said pipette to said at least one dilutor means, and a pressure sensor is provided in communication with said lead and said dilutor means.

9. A specimen distributing apparatus in accordance with claim 8, additionally comprising a vibration imparting device and a vibration sensing device in communication with each said pipette, and a comparator means which compares the nominal frequency to the measured frequency of the end of each said pipette.

10. A specimen distribution apparatus for automated extraction of specified quantities of sample specimens from primary containers and transfer of said sample specimens to secondary containers for testing, said apparatus comprising:

a circular table rotatable about a central vertical axis;

a plurality of manipulator units supported on said table and spaced a radial distance from said central vertical axis, each said manipulator unit movable back and forth in a linear direction perpendicular to the radius of said table and each said manipulator unit supporting at least one pipette movable in vertical direction;

a plurality of said primary containers forming a primary container assembly, said primary container assembly radially arranged with respect to said central vertical axis, extending beyond the circumference of and radially movable with respect to said central vertical axis of said table;

a plurality of said secondary containers forming secondary container assemblies, each said secondary container assembly arranged radially with respect to said central vertical axis, extending beyond said circumference of and radially movable with respect to said central vertical axis of said table and circumferentially aligned with said primary container assembly; and

a washing device for cleaning said pipettes circumferentially aligned with said primary and said secondary container assemblies and between the last said secondary container assembly and said primary container assembly with respect to said rotatable direction of said table, each said manipulator unit comprises a vertically oriented support with a horizontally oriented cross-piece extending beyond said circumference of said table over one of said container assemblies, said vertically oriented support is movable back and forth on a guide unit aligned perpendicular to the radius of said table, and said horizontally oriented cross-piece supports said at least one pipette and is vertically adjustable on said vertically oriented support.

11. A specimen distribution apparatus for automated extraction of specified quantities of sample specimens from primary containers and transfer of said sample specimens to secondary containers for testing, said apparatus comprising:

a circular table rotatable about a central vertical axis;

a plurality of manipulator units supported on said table and spaced a radial distance from said central vertical axis, each said manipulator unit movable back and forth in a linear direction perpendicular to the radius of said table and each said manipulator unit supporting at least one pipette movable in vertical direction;

a plurality of said primary containers forming a primary container assembly, said primary container assembly radially arranged with respect to said central vertical axis, extending beyond the circumference of and radially movable with respect to said central vertical axis of said table;

a plurality of said secondary containers forming secondary container assemblies, each said secondary container assembly arranged radially with respect to said central vertical axis, extending beyond said circumference of and radially movable with respect to said central vertical axis of said table and circumferentially aligned with said primary container assembly, said primary and secondary container assemblies are movable in a radial direction with respect to said central vertical axis; and

a washing device for cleaning said pipettes circumferentially aligned with said primary and said secondary container assemblies and between the last said secondary container assembly and said primary container assembly with respect to said rotatable direction of said table.