Plaster structural assembly for iontophoresis

• US 4,842,577 A
• Filed: 10/16/1987
• Issued: 06/27/1989
• Est. Priority Date: 10/20/1986
• Status: Expired due to Fees

• Current Assignee: Yamanouchi Pharmaceutical Co., Ltd. (Astellas Pharma Incorporated)
• Original Assignee: Yamanouchi Pharmaceutical Co., Ltd. (Astellas Pharma Incorporated)
• Inventors: Mitomi, Mitsuo, Konno, Yutaka, Sonobe, Takashi, Yamaguchi, Shumpei
• Primary Examiner(s): Niebling, John F.
• Assistant Examiner(s): STARSIAK, JOHN S
• Application Number:
  US07/109,083
• Time in Patent Office: 620 Days
• Field of Search: 204/299 R, 604/20, 128/789, 128/802, 128/803
• US Class Current: 604/20
• CPC Class Codes: A61N 1/0436 Material of the electrode
• CPC Class Codes: A61N 1/0448 Drug reservoir

Abstract

A novel plaster structural assembly is provided for iontophoresis wherein th e assembly is comprised of an electrode layer and a medicament-containing layer in which a water supplying layer is disposed between the electrode layer and the medicament-containing layer with a sealing cover disposed on the outside of the electrode layer. A method for using the structural assembly for iontophoresis is also provided.

Claims

1. A plaster structural assembly for iontophoresis comprising an electrode layer and a medicament containing layer, wherein a water supplying layer is disposed between the electrode layer and the medicament-containing layer and further a sealing cover is formed at the outside of the electrode layer, said water supplying layer composed of water and water retentive fibers.

2. A plaster structural assembly for iontophoresis comprising an electrode layer and a medicament containing layer, wherein a water supplying layer is disposed between the electrode layer and the medicament-containing layer,

said water supplying layer being composed of a water-containing self adhesive layer and a water-containing layer,

and further a sealing cover is formed at the outside of the electrode layer.

3. The plaster structural assembly as claimed in claim 2, wherein the thickness of the medicament-containing layer is from 0.1 mm to 1.0 mm.

5. A method for administering a medicament to a subject in need of such medicament by absorption of said medicament by iontophoresis, said method comprising contacting the skin of said subject with the plaster structural assembly of claim 2 and thereafter applying an electric current.

4. The plaster structural assembly as claimed in claim 8 wherein the medicament-containing layer is from about 1/2 to about 1/3 of the area of said water-containing self adhesive layer.