Sucrose fatty acid ester coated suture

• US 4,844,067 A
• Filed: 02/09/1988
• Issued: 07/04/1989
• Est. Priority Date: 02/19/1987
• Status: Expired due to Term

• Current Assignee: JMS Company Limited
• Original Assignee: Bio-Materials Univers Company, Gunze Limited, Medical Supply Depot
• Inventors: Ikada, Yoshito, Gen, Shokyu, Matsuda, Takashi, Kawai, Tatsuya
• Primary Examiner(s): Apley, Richard J.
• Assistant Examiner(s): NOT, DEFINED
• Application Number:
  US07/153,996
• Time in Patent Office: 511 Days
• Field of Search: 128/335.5, 128/334, 623/11, 623/13, 623/66, 524/306, 536/119, 427/2
• US Class Current: 606/231
• CPC Class Codes: A61L 17/145 Coating

Abstract

A suture coating composition comprising a sucrose fatty acid ester and sutures coated therewith whereby said sutures exhibit improved smoothness in tie-down properties and knotting can be readily accomplished using said suture.

Claims

1. A suture coated with a composition consisting essentially of sucrose fatty acid ester.

2. A suture according to claim 1 wherein said sucrose fatty ester comprises a fatty acid selected from the group consisting of stearic acid, palmitic acid, lauric acid, myristic acid, and mixtures thereof.

3. A suture according to claim 1 wherein said sucrose fatty acid ester comprises an ester selected from the group consisting of monoester, diester, polyester and mixtures thereof.

4. A suture according to claim 3 wherein said sucrose fatty acid ester exhibits a hydroxyl value of less than about 130.

5. A suture according to claim 6 wherein said sucrose fatty acid ester comprises a fatty acid selected from the group consisting of stearic acid, palmitic acid, lauric acid, myristic acid and mixtures thereof in admixture with acetic acid or butyric acid.

6. A suture according to claim 1 wherein said suture comprises homopolymer and copolymers of lactide, glycolide, 8-hydroxybutylcarboxylic acid, β

-propiolactone, γ

-butyrolactone, γ

-valero-3-methylbutyrolactone, δ

-valerolactone, chitin, and ξ

-caprolactone.

7. A suture according to claim 6 wherein said suture comprises homopolymers or copolymers of glycolide.

8. A suture according to claim 1 wherein said suture comprises silk, nylon or polyester.