Non-invasive collection means and method
First Claim
1. A device for use in a non-invasive method of collecting a tissue fluid sample from a human or an animal which comprises a probe having at one end a relatively rigid member for forming a contusion on the skin of said human or animal, a cup-shaped member surrounding the relatively rigid member for forming a seal with the skin about the outside of the contusion, a sealed vacuum tube in the other end of the probe, a passage in the probe extending from the cup-shaped member to means for opening the seal of the vacuum tube and a one-way valve in said passage permitting flow from the probe tip to the vacuum tube but not in the other direction.
2 Assignments
0 Petitions
Accused Products
Abstract
A non-invasive method for collecting tissue fluids from a human or an animal which comprises pretreating the external surface of an area of the skin of the human or the animal with a solution to clean off dead cells, forming a liquid coating over the skin, forming a superficial contusion on that area of the skin without nicking or piercing the skin, sealing that area of the skin and then collecting tissue fluid from the area of the contusion with the assistance of vacuum. The tissue fluid collected may be used for diagnostic purposes. A device for practicing the method is also disclosed.
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Citations
3 Claims
- 1. A device for use in a non-invasive method of collecting a tissue fluid sample from a human or an animal which comprises a probe having at one end a relatively rigid member for forming a contusion on the skin of said human or animal, a cup-shaped member surrounding the relatively rigid member for forming a seal with the skin about the outside of the contusion, a sealed vacuum tube in the other end of the probe, a passage in the probe extending from the cup-shaped member to means for opening the seal of the vacuum tube and a one-way valve in said passage permitting flow from the probe tip to the vacuum tube but not in the other direction.
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3. A non-invasive method for collection of tissue fluid from an animal which comprises pretreating an external surface of a selected area of the skin of the animal to clean off dead cells, applying a probe containing a coating liquid to the selected area of the skin, retaining the liquid on the selected area with the probe, forming a superficial contusion on that area of the skin without removing the probe and without nicking or piercing the skin, and then collecting any tissue fluid and said coating liquid from the area of the contusion with vacuum assistance.
Specification