Blood parameter monitoring apparatus and methods

• US 4,846,183 A
• Filed: 12/02/1987
• Issued: 07/11/1989
• Est. Priority Date: 12/02/1987
• Status: Expired due to Fees

• Current Assignee: Datex-Ohmeda Incorporated (General Electric Company)
• Original Assignee: BOC Group Pty Limited (Linde Plc)
• Inventors: Martin, Alan D.
• Primary Examiner(s): CHAMBERS, A MICHAEL
• Application Number:
  US07/127,741
• Time in Patent Office: 587 Days
• Field of Search: 128/633, 356/41, 364/416
• US Class Current: 600/336
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: G01N 21/3151 using two sources of radiation of different wavelengths G01N21/33 - G01N21/39 take precedence

Abstract

A pulse oximeter or plethysmographic device utilizes light varying in intensity at a predetermined carrier frequency. A passive resonant circuit having a resonant frequency substantially equal to the carrier frequency is connected between the photodetector and the first amplifier. The resonant circuit serves to suppress spurious DC and low frequency components such as those due to ambient light and ambient light flicker and also to suppress high frequency interference. Because ambient light signals are suppressed, there is no need for dark current correction or restoration. Suppression of ambient light and other interference upstream of the front end amplifier avoids saturation of the amplifier and permits use of a front end amplifier having high gain.

Claims

1. Apparatus for monitoring a parameter of the blood within a body structure comprising:

(a) illumination means for emitting light at at least one wavelength and directing the emitted light through said body structure;

(b) photodetector means for detecting light from said illumination means transmitted through said body structure and producing at least one photodetector signal representing the intensity of said detected light;

(c) carrier frequency means for varying the amplitude of the light emitted by said illumination means at at least one carrier frequency whereby said at least one photodetector signal will include at least one component at said at least one carrier frequency bearing information relating to the optical transmissivity of said body structure at said at least one wavelength;

(d) modification means for modifying said at least one photodetector signal by passing and attenuating components of said at least one photodetector signal dependent upon their respective frequencies so as to increase the ratio of said at least one carrier frequency component relative to other components and thereby provide at least one modifed signal;

(e) amplification means for amplifying each said modified signal to provide at least one amplified signal; and

(f) interpretation means for determining said parameter of the blood in said body structure from said at least one amplified signal.

2. Apparatus for monitoring a parameter of the blood within a body structure comprising:

(a) illumination means for emitting light at at least one wavelength and directing the emitted light through said body structure;

(b) photodetector means for detecting light from said illumination means transmitted through said body structure and producing at least one photodetector signal representing the intensity of said detected light;

(c) carrier frequency means for varying the amplitude of the light emitted by said illumination means at at least one carrier frequency whereby said at least one photodetector signal will include at least one component at said at least one carrier frequency bearing information relating to the optical transmissivity of said body structure at said at least one wavelength;

(d) modification means for modifying said at least one photodetector signal to increase the ratio of said at least one carrier frequency component relative to other components and thereby provide at least one modified signal;

(e) amplification means for amplifying each said modified signal to provide at least one amplified signal; and

(f) interpretation means for determining said parameter of the blood in said body structure from said at least one amplified signal,

said modification means including at least one passive resonant circuit having a resonant frequency substantially equal to each said carrier frequency.

3. Apparatus as claimed in claim 2, wherein said illumination means includes means for emitting light at a plurality of wavelengths and said interpretation means includes means for determining the level of a constituent of the blood.

4. Apparatus as claimed in claim 3 wherein said carrier frequency means includes means for varying the amplitude of light at all of said plurality of wavelengths emitted by said illumination means at a single carrier frequency, said modification means includes a single passive resonant circuit having a resonant frequency substantially equal to said single carrier frequency, said amplification means includes means for amplifying said modified signal from said single resonant circuit to provide a single amplified signal.

5. Apparatus as claimed in claim 4 further comprising timing means for actuating said illumination means to emit light of each of said plurality of wavelengths at different times according to a predetermined time division schedule so that different times are associated with different wavelengths, said interpretation means including means for recovering information relating to the optical transmissivity of said body structure at each said wavelength from those portions of said amplified signal occurring during the times associated with that wavelength.

6. Apparatus as claimed in claim 5 wherein said single resonant circuit is damped.

7. Apparatus as claimed in claim 6 wherein said timing means includes means for providing bursts of light having said different wavelengths in alternating sequence at a predetermined switching frequency lower than said carrier frequency and wherein said interpretation means includes means for rejecting portions of said amplified signal occurring during the first portion of each such burst.

8. Apparatus as claimed in claim 7 wherein said timing means is arranged to provide said bursts in immediate succession so that a burst of one wavelength follows immediately after a burst of another wavelength.

9. Apparatus as claimed in claim 8 wherein said means for rejecting includes means for sampling said amplified signal during each said burst from said illumination means only after a predetermined delay time has elapsed after the start of the burst, to provide a sampled signal, said interpretation means including means for recovering said information from said sampled signal.

10. Apparatus as claimed in claim 9 wherein said means for recovering information from said sampled signal includes separate signal processing channels associated with each of said wavelengths, said sampling means including means for directing samples of said amplified signal taken during each said burst to the channel associated with the wavelength of such burst.

11. Apparatus as claimed in claim 10 wherein said sampling means includes separate means for sampling said amplified signal during bursts of each said wavelength.

12. Apparatus as claimed in claim 10 wherein each said signal processing channel includes low-pass filter means for eliminating components at and above said switching frequency from the sampled signal in such channel to provide a filtered signal.

13. Apparatus as claimd in claim 12 wherein said interpretation means includes means for capturing the DC and AC components in said filtered signal in each said channel and interpreting said DC and AC components as the DC and AC components respectively, of the transmissivity of said body structure associated with that channel.

14. Apparatus as claimed in claim 2, wherein said photodetector means includes a photoelectric element having an output node connected to said amplification means and said at least one passive resonant circuit includes an inductor and a capacitor connected in parallel to said output node.

15. Apparatus as claimed in claim 14 wherein said photoelectric element includes a photoconductive diode.

16. Apparatus as claimed in claim 15 wherein further comprising bias means for supplying a bias voltage to said photoconductor.

17. A method of monitoring a parameter of the blood within a body structure comprising the steps of:

(a) emitting light at at least one wavelength while varying the amplitude of the emitted light at at least one carrier frequency and directing the emitted light through the body sturcture;

(b) detecting light transmitted through the body structure and producing at least one photodetector signal representative of the detected light and having at least one component at each said carrier frequency;

(c) modifying said at least one photodetector signal by passing and attenuating components of said at least one photodetector signal depending upon their respective frequencies so as to increase the ratio of said at least one carrier frequency component to other components and thereby provide at least one modified signal;

(d) amplifying said at least one modified signal to provide at least one amplified signal; and

(e) determining said parameter from said at least one amplified signal.

19. A method as claimed in claim 17 wherein said parameter is the level of a constituent in the blood and said light emitting step includes the step of emitting light at a plurality of wavelengths.

18. A method of monitoring a parameter of the blood within a body structure comprising the steps of:

(a) emitting light at at least one wavelength while varying the amplitude of the emitted light at at least one carrier frequency and directing the emitted light through the body structure;

(b) detecting light transmitted through the body structure and producing at least one photodetector signal representative of the detected light and having at least one component at each said carrier frequency;

(c) modifying said at least one photodetector signal to increase the ratio of said at least one carrier frequency component to other components and thereby provide at least one modified signal;

(d) amplifying said at least one modified signal to provide at least one amplified signal; and

(e) determining said parameter from said at least one amplified signal, said amplifying step including the step of passing said photodetector signal to an input node of an amplifier, and said attenuating step includes the step of maintaining a passive circuit resonant at said at least one carrier frequency in parallel with said amplifier input node.