Electroencephalographic system data display

• US 4,846,190 A
• Filed: 04/30/1987
• Issued: 07/11/1989
• Est. Priority Date: 08/23/1983
• Status: Expired due to Term

• Current Assignee: New York University
• Original Assignee: Erwin R. John
• Inventors: John, Erwin R.
• Primary Examiner(s): Jaworski, Francis
• Assistant Examiner(s): MANUEL, GEORGE C
• Application Number:
  US07/044,438
• Time in Patent Office: 803 Days
• Field of Search: 128/731, 128/732, 128/733
• US Class Current: 600/544
• CPC Class Codes: A61B 5/301 providing electrical separation, e.g. by using isolating transformers or optocouplers
• CPC Class Codes: A61B 5/319 Circuits for simulating ECG signals
• CPC Class Codes: A61B 5/369 Electroencephalography [EEG] devices for psychotechnics A61B5/16
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61B 5/743 Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots

Abstract

An EEG (electroencephalograph) system detects a patient'"'"'s brain waves from electrodes pressed against the patient'"'"'s scalp, amplifies the analog brain waves and converts them into digital signals. The digital brain waves are processed to reduce electrical interference, muscle artifact and other noise, and then compared on a statistical basis against the patient'"'"'s self-norm and population norms derived from groups of normal and abnormal groups of patients under specified conditions. The results of the statistical analysis, on an almost real-time basis, are displayed on a CRT color monitor. Two alternative embodiments of displays are:

(1) Sequential analyses of time segments, intensity modulated to reflect statistical significance, are displayed in eight areas corresponding to eight brain sectors using a moving window type of histogram, stacked from top to bottom in temporal sequence;

(2) Lights are laid out on a control console in the form of a topographic head map and the color of the lights is coded to correspond with the results of statistical analysis.

Claims

1. An electroencephalographic (EEG) system including:

brain wave signal means to detect and amplify brain waves from the head of a patient, comprising a plurality of electrodes removably attached to a plurality of sectors of the patient'"'"'s head to detect signals representing said brain waves, amplifiers connected to the electrodes, and analog/digital conversion means connected to the amplifiers to produce sets of digital data representing said brain waves from a selected plurality of sectors of the patient'"'"'s head;

memory means to store selected reference normative data, said normative data being selected from the group of data for some prior state of the patient and data of population norms;

data analysis means connected to said brain wave signal means and said memory means to analyze the said brain wave signals on a statistical basis as compared to said reference normative data to produce a plurality of analysis samples; and

display means connected to said data analyses means to visually display said analysis, characterized in that the display means comprises means to display said plurality of analysis samples as a plurality of rectangular stripes and means to modulate said stripes so that each of the stripes is modulated to represent the result of the said statistical analysis, the modulation being from the group of gray-scale code and color-code whose modulation is coded to the significance of the said statistical analysis; and

means to form said stripes into a pile of said stripes, said pile having opposite ends with an oldest-in-time stripe at one end, and a youngest-in-time stripe at the opposite end, said pile forming a moving window display in which the oldest-in-time stripe at one end of the pile is removed and replaced by a new youngest-in-time stripe at the opposite end of the pile.

2. An EEG system as in claim 1 wherein the display means includes a head diagram having display sectors representing a plurality of head sectors, said stacks form a plurality of said moving window displays, each one of the said moving window displays being shown in each display sector to provide information concerning the brain waves occurring in the corresponding region of the patient'"'"'s head represented by the display sector.

3. An EEG system as in claim 2 wherein the electrodes consist of four pairs of electrodes to detect brain waves in eight head sectors.

4. An EEG system as in claim 1 wherein said data analysis means includes means to perform a spectral analysis of a selected frequency band of data.

5. An EEG system as in claim 4 wherein said spectral analysis means is a Fourier Transform means.

6. An EEG system as in claim 1 wherein the display means includes means to display a border around said stack, and means to flash the border as an alarm for conditions which are abnormal compared to said reference normative data.

7. An electroencephalograph (EEG) system including:

brain wave signal means to detect and amplify the waves from the head of a patient comprising a plurality of electrodes adapted to be connected to the patient'"'"'s head to detect signals representing said brain waves, amplifiers connected to the electrodes, and analog/digital conversion means connected to the amplifiers to produce sets of digital data representing said brain waves from a plurality of sectors of the head;

data analysis means connected to said brain wave signal means to analyze the said brain wave signals on a statistical basis in comparison to a set of normative data;

display means connected to said data analysis means to visually display the results of said analysis;

the data being displayed in the form of a topological map with each area of the map corresponding in location to a sector of the patient'"'"'s head;

characterized in that;

the said areas are blocks, each of which blocks having a plurality of sub-areas which are arranged in sub-areas formed in rows and columns, with rows representing sequential analyses and columns representing different measures, and with gaps between the blocks;

each of the sub-areas of the blocks is color-coded so that its color is directly related to the result of said statistical analysis of the corresponding head sector within or across measures.

8. An EEG system as in claim 7 wherein the display means includes means to display a border about each of the said blocks and means to flash the border on-off as a warning signal for a condition which is abnormal compared to said reference normative data.

9. An EEG system as in claim 7 and further characterized in that a plurality of color-coded row bars extend between the blocks of each row, and the system includes means to control the color of the row bars so that their color is a display of the results of statistical analysis on the relationships between the head sectors corresponding to the blocks of said rows.

10. An EEG system as in claim 7 and further characterized in that a plurality of color-coded column bars extend between the blocks of each column, and the system includes means to control the color of the column bars so that their color is a display of the results of statistical analysis on the relationships between the head areas corresponding to the blocks of said columns.

11. An electroencephalograph (EEG) system including:

brain wave signal means to detect and amplify the brain waves from the head of a patient comprising a plurality of electrodes adapted to be connected to the patient'"'"'s head to detect signals representing the said brain waves, amplifiers connected to the electrodes, and analog/digital conversion means connected to the amplifiers to produce sets of digital data corresponding to the patient'"'"'s brain waves from a plurality of sectors of the patient'"'"'s head;

memory means to store reference normative data selected from the group of some prior state of the patient and population norms;

data analysis means connected to said brain wave signal means and to said memory means to analyze the said brain wave signals on a statistical basis on comparison to said normative data;

display means including a CRT screen to visually display said analysis;

wherein the data is displayed in the form of a topological map in which each area of the map corresponds in location to a sector of the patient'"'"'s head;

characterized in that;

the said areas on the CRT screen are arranged in rows and columns, each of the areas consisting of a separated shape with gaps between said shapes and each shape representing the EEG feature derived from the group of the complete energy spectrum of brain waves, the absolute or relative (%) power from one or more frequency bands, coherence as between one or more frequency bands, and asymmetry as between frequency bands; and

the system includes;

means to color-code each of the shapes so that the color of said shape is directly related to the result of said statistical analysis of the EEG factor at the corresponding head sector or the relations between two sectors and

means to display on said CRT screen a plurality of color-coded bars connecting the said areas and means to control the color of the said bars to display relationships between the said areas.

12. An EEG system as in claim 11 wherein each of the areas consists of sub-areas comprising a plurality of geometric shapes arranged in rows and columns with the rows indicating the said analysis results over a tandem series of time periods, and the columns representing different extracted features and the shape being selected from the group of dots, bar and line segments.

13. An EEG system as in claim 11 and further including means to display a border about each of the said areas, and means to flash the border on-off as a warning signal.

14. An EEG system as in claim 11 and further including means to selectively display the areas or bars separately or superimposed on each other on said display.

15. An electroencephalograph (EEG) system including:

brain wave signal means to detect and amplify the brain waves from the head of a patient comprising a plurality of electrodes, each electrode being adapted to be connected to a sector of the patient'"'"'s head to detect signals representing the patient'"'"'s brain waves at the sector to which it is connected, amplifiers connected to the electrodes, an analog/digital conversion means connected to the amplifiers to produce sets of digital data representing the patient'"'"'s brain waves from the said head sectors;

data analysis means connected to said conversion means to analyze the digital brain wave signals on a statistical basis in comparison to a set of stored normative data to produce a head sector relationship analysis which is a statistical analysis of the coherence relationship between the brain waves from each head sector and the brain waves from every other head sector, in a selected frequency band;

display means connected to said data analysis means to visually display the results of the said head sector coherence analysis;

wherein the said analysis is displayed in the form of a topological map in which each area of the map corresponds in location to a patient head sector;

wherein;

the said map areas at least twenty map areas are arranged such that each of the map areas is itself arranged as an array of dots representing the position of each electrode, with one dot representing a head sector and the other dots representing the said statistical analysis of the coherence between the sector represented by the said one dot and the other head sectors, in any selected frequency band,

and the system further including;

means to color-code each of the dots so that its color corresponds to the result of said statistical coherence analysis.

16. An EEG system as in claim 15 wherein each of the dots is a rectangle.

17. An EEG system as in claim 15 wherein the display is of a plurality of the said maps, each of said maps indicating the relationship between the head sectors.

18. An EEG system as in claim 17 wherein the measures are selected from the group consisting of absolute power and relative power in at least four frequency bands.

19. An EEG system as in claim 17 wherein the system includes computer means to subject the power data to Z-transformation based upon computer stored norms.

20. An EEG system as in claim 15 wherein said data analysis means includes a spectral analysis means to analyze data selected from the group of the full spectrum of the waves, at least four absolute power frequency bands, at least four relative power frequency bands, and frequency amplitude spectrum coherence as between at least four frequency bands.