Antimicrobial compositions consisting of metallic silver combined with titanium oxide or tantalum oxide
First Claim
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1. An antimicrobial composition for use in contact with materials which cause or are susceptible to bacterial infection by body fluids or tissue, said composition comprising metallic silver as the antimicrobial agent together with an oxide component selected from the group consisting of titanium and tantalum oxides present in an amount effective to provide release of silver ions into surrounding tissue or fluid.
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Abstract
An antimicrobial composition which includes silver as the antimicrobial agent also includes a hydratable or hydrated oxide as a promoter to enhance the antimicrobial effect. Such compositions may be used to coat appliances such as catheters or may be incorporated in bone cements.
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11 Claims
- 1. An antimicrobial composition for use in contact with materials which cause or are susceptible to bacterial infection by body fluids or tissue, said composition comprising metallic silver as the antimicrobial agent together with an oxide component selected from the group consisting of titanium and tantalum oxides present in an amount effective to provide release of silver ions into surrounding tissue or fluid.
- 4. An antimicrobial composition according to in which the silver is deposited on particles of titanium dioxide.
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9. In an antimicrobial composition comprising metallic silver as the antimicrobial agent and wherein the activity of said agent is undesirably affected in contact with body fluids, the improvement which comprises including in said composition titanium dioxide to enhance the activity of said agent.
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10. In a method wherein metallic silver is used as an antimicrobial agent in the presence of fluids which tend to undesirably affect the antimicrobial activity of the silver, the improvement which comprises including titanium dioxide with the metallic silver to stabilize the activity of the silver against said fluids and to provide release of silver ions into the fluid to produce a sustained antimicrobial effect.
Specification