Chewable medicament tablet containing means for taste masking

• US 4,851,226 A
• Filed: 06/30/1988
• Issued: 07/25/1989
• Est. Priority Date: 11/16/1987
• Status: Expired due to Term

• Current Assignee: Personal Products Co. (Johnson & Johnson)
• Original Assignee: McNeil Consumer Products Co. (Johnson & Johnson)
• Inventors: Julian, Thomas N., Radebaugh, Galen W.
• Primary Examiner(s): Page, Thurman K.
• Assistant Examiner(s): HORNE, LEON
• Application Number:
  US07/214,265
• Time in Patent Office: 390 Days
• Field of Search: 424/441, 424/470, 424/472, 424/480, 424/482, 424/494, 424/497
• US Class Current: 424/441
• CPC Class Codes: A61K 9/0056 Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
• CPC Class Codes: A61K 9/5026 obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
• CPC Class Codes: A61K 9/5042 Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose

Abstract

Chewable medicament tablets are made from coated granules of medicament wherein the coating on said granules comprises a blend of cellulose acetate or cellulose acetate butyrate and polyvinyl pyrrolidone.

Claims

1. A chewable tablet of a medicament comprising compressed coating granules, said coated granules individually comprising medicament coated with a blend of (a) cellulose acetate or cellulose acetate butyrate and (b) polyvinyl pyrrolidone.

2. The chewable tablet of claim 1 wherein the medicament is acetyl p-aminophenol.

3. The chewable tablet of claim 1 wherein the blend contains from about 80 to about 97 weight percent of cellulose acetate, the remainder being polyvinyl pyrrolidone.

4. The chewable tablet of claim 2 wherein the blend contains from about 80 to about 97 weight percent of cellulose acetate, the remainder being polyvinyl pyrrolidone.

5. The chewable tablet of claim 1 wherein the coated granules contain from about 5 to about 20 weight percent of said blend.

6. The chewable tablet of claim 2 wherein the coated granules contain from about 5 to about 20 weight percent of said blend.

7. The chewable tablet of claim 3 wherein the coated granules contain from about 5 to about 20 weight percent of said blend.

8. The chewable tablet of claim 4 wherein the coated granules contain from about 5 to about 20 weight percent of said blend.