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Drug delivery system with means for obtaining desirable in vivo release rate pattern

  • US 4,851,232 A
  • Filed: 06/08/1987
  • Issued: 07/25/1989
  • Est. Priority Date: 02/13/1987
  • Status: Expired due to Fees
First Claim
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1. A drug delivery device for the controlled delivery of a beneficial drug to an environment of use over a prolonged period of time, the delivery device comprising:

  • (a) a reservoir comprising a pharmaceutically acceptable hydroxypropylmethylcellulose; and

    ,(b) a plurality of tiny pills housed in the reservoir, the tiny pills comprising;

    (1) a core of a beneficial drug; and

    ,(2) a wall comprising in at least a part a drug release rate controlling cellulosic polymer comprising an acetyl content of 21 to 44.8% that surrounds the core of the beneficial drug and releases the drug when the device is in use in the environment of use.

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