Device comprising means for protecting and dispensing fluid sensitive medicament
First Claim
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1. A device for delivering porcine somatotropin to a pig, the device comprising:
- (a) a wall that surrounds;
(b) an internal space;
(c) means in the wall for connecting the exterior of the device with the internal space;
(d) a composition in the space comprising porcine somatotropin and a pharmaceutically acceptable polyol and(e) a composition in the space comprising means for diminishing the volume occupied by the composition comprising the porcine somatotropin, thereby delivering the porcine somatotropin to the pig.
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Abstract
A delivery device is disclosed for delivering a beneficial agent to an animal. The device comprises a wall housing an internal space, a beneficial agent in the space, expandable means in the space for causing the beneficial agent to be delivered from the device and means in the space for shielding the beneficial agent from fluid.
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Citations
8 Claims
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1. A device for delivering porcine somatotropin to a pig, the device comprising:
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(a) a wall that surrounds; (b) an internal space; (c) means in the wall for connecting the exterior of the device with the internal space; (d) a composition in the space comprising porcine somatotropin and a pharmaceutically acceptable polyol and (e) a composition in the space comprising means for diminishing the volume occupied by the composition comprising the porcine somatotropin, thereby delivering the porcine somatotropin to the pig.
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2. A device for delivering a somatotropin to livestock, the device comprising:
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(a) a wall; (b) a lumen defined by the wall; (c) means in the wall for connecting the exterior with the interior of the device; (d) a composition in the lumen comprising a somatotropin and a member selected from the group consisting of 1,5-pentylene glycol, 1,6-hexylene glycol, 1,7-heptylene glycol, 1,9-nonylene glycol, 1,2-dimethyl-1,6-hexylene glycol, 1,2,3-propanetriol, 1,2,5-pentanetriol, 1,3,5-pentanetriol, 1,2,4-butanetriol and dipentaerythriol; and
;(e) a composition in the lumen comprising means for diminishing the volume occupied by the composition comprising the somatotropin for delivering the somatotropin to the livestock.
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3. A device for delivering in vivo a somatotropin to an animal, the device comprising:
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(a) a wall; (b) a lumen defined by the wall; (c) means in the device for connecting the exterior with the interior of the device; (d) a composition in the lumen comprising a somatotropin and pharmaceutically acceptable member selected from the group consisting of a diol, a triol, a polyol and a polyhydric alcohol; (e) a composition in the lumen comprising means for diminishing the volume occupied by the composition comprising the somatotropin for delivering the somatotropin to the animal; and
,(f) composition means between (d) and (e) for maximizing the delivery of somatotropin from the device to the animal over time.
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4. A device for delivering a beneficial agent to an animal, wherein the device comprises:
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(a) a wall; (b) an internal lumen defined by the wall; (c) exit means in the wall for connecting the exterior with the interior of the device; (d) a beneficial agent composition in the lumen comprising a somatotropin and a pharmaceutically acceptable carrier; (e) driving means in the lumen for decreasing the space occupied by the beneficial agent composition; and
,(f) means between the beneficial agent composition and the driving means for insuring the force generated by the driving means is applied against the beneficial agent composition for delivering the somatotropin to the animal.
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5. A device for delivering somatotropin to an environment of use, wherein the device comprises:
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(a) a wall; (b) an internal lumen defined by the wall; (c) exit means for connecting the exterior and the interior of the device; (d) a somatotropin in the lumen; (e) means for protecting the somatotropin from the environment of use; and
,(f) means in the lumen for occupying the space occupied by the somatotropin. - View Dependent Claims (6, 7, 8)
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Specification