Laser method and apparatus for the recanalization of vessels and the treatment of other cardiac conditions

• US 4,860,743 A
• Filed: 06/03/1987
• Issued: 08/29/1989
• Est. Priority Date: 10/27/1986
• Status: Expired due to Term

• Current Assignee: University of Florida Research Foundation, Incorporated (State University System of Florida)
• Original Assignee: University of Florida (State University System of Florida)
• Inventors: Abela, George S.
• Primary Examiner(s): HINDENBURG, MAX F
• Application Number:
  US07/056,878
• Time in Patent Office: 818 Days
• Field of Search: 128/4-8, 128/303.1, 128/395-398, 128/734
• US Class Current: 606/7
• CPC Class Codes: A61B 18/245 for removing obstructions in blood vessels or calculi
• CPC Class Codes: A61B 2017/00026 Conductivity or impedance, e.g. of tissue
• CPC Class Codes: A61B 2017/00247 Making holes in the wall of the heart, e.g. laser Myocardial revascularization
• CPC Class Codes: A61B 2018/00392 Transmyocardial revascularisation
• CPC Class Codes: A61B 2018/2261 with scattering, diffusion or dispersion of light
• CPC Class Codes: A61B 2562/043 in a linear array
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]

Abstract

Cardiac conditions such as blockages in arteries caused by plaque build-up are treated intravascularly with laser radiation using an optical fiber having a heat conducting end cap on its distal end. A spherical lens within the end cap focuses a small portion of the laser energy directly into the plaque which is in contact with the tip of the end cap and disperses the remaining energy into the end cap for heating it up. The direct laser energy vaporizes part of the plaque so that the end cap can be easily forced through the blockage, and the tissue in contact with the heated end cap is burned away. A diffuser catheter for the ablation of electrical conduction tissue in the heart employs spaced electrodes for detecting the presence of the conduction tissue, and directs laser energy outwardly through the side of the catheter for vaporizing the tissue.

Claims

1. Apparatus for treating cardiac conditions with laser radiation comprising a catheter adapted to be inserted into a blood vessel and threaded through the blood vessel to a region to be treated, the catheter comprising a tubular body having a window of laser radiation transparent material formed in a sidewell thereof;

an optical fiber for guiding a laser beam disposed within the catheter, the optical fiber having an end terminating adjacent to said window; and

lens means on the end of the optical fiber for dispersing a laser beam guided by the optical fiber sideways outwardly through said window for treating tissue adjacent to the window and wherein said window comprises a closed tubular section of said transparent material which is coaxially disposed between a first catheter body section and a second catheter body section, said optical fiber entering the closed tubular section and terminating therein and wherein said closed tubular section has a cylindrical inner surface which is mirrored except for a part thereof which forms said window so as to reflect the laser beam from the optical fiber outwardly through the window.

2. Apparatus for treating cardiac conditions with laser radiation comprising a catheter adapted to be inserted into a blood vessel and threaded through the blood vessel to a region to be treated, the catheter comprising a tubular body having a window of laser radiation transparent material formed in a sidewall thereof;

an optical fiber for guiding a laser beam disposed within the catheter, the optical fiber having an end terminating adjacent to said window; and

lens means on the end of the optical fiber for dispersing a laser beam guided by the optical fiber sideways outwardly through said window for treating tissue adjacent to the window, and further comprising first and second electrode means disposed about the tubular catheter body on opposite sides of the window for detecting the presence of conductive tissue adjacent to said window.

3. The apparatus of claim 2 wherein said catheter has a closed distal end.

4. The apparatus of claim 2 wherein said window comprises a closed tubular section of said transparent material which is coaxially disposed between a first catheter body section and second catheter body section, and optical fiber entering the closed tubular section and terminating therein.

5. The apparatus of claim 4 further comprising radiation-dispersing microspheres disposed within the closed tubular section for dispersing the laser beam from the optical fiber.

6. The apparatus of claim 5 wherein said microspheres are made of material selected from the group comprising glass and plastic.

7. The apparatus of claim 2 wherein said optical fiber includes a core and a cladding, and wherein said core is exposed along a length thereof adjacent to the window such that alight from a laser beam may pass from the exposed length of the core to the window.

8. A method for the ablation of electrical conduction tissue in a heart comprising threading a catheter through a blood vessel into the heart, the catheter carrying an optical fiber and having first and second spaced electrodes located on a peripheral surface of the catheter;

positioning the catheter such that the electrodes contact tissue;

detecting the presence of electrical conduction tissue in contact with the electrodes;

supplying laser energy to the optical fiber for transmission to the location of the electrodes; and

causing the laser energy transmitted by the optical fiber to be emitted sideways outwardly from a part of the catheter disposed between the spaced electrodes and into said conduction tissue.

9. The method of claim 8, wherein said causing comprises dispersing the laser energy emitted from a length of the optical fiber located between the spaced electrodes outwardly through a window in a sidewall of the catheter.

10. The method of claim 9, wherein said dispersing comprises reflecting the laser energy such that all of the laser energy is emitted through said window.